LTRL590_350005500

2-oxoisovalerate dehydrogenase beta subunit, mitochondrial precursor, putative
Leishmania tropica L590 OG6: OG6_101601 OG7: OG7_0003147 29 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 29 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_010005400 ⚠
carboxylase, putative
— OG6
LTRL590_360043600 ⚠
Bromodomain, putative
— OG7
LTRL590_270018300 ⚠
Carboxypeptidase Taq (M32) metallopeptidase,
— OG7
LTRL590_290030000 ⚠
aminopeptidase, putative
— OG7
LTRL590_120014700 ⚠
puromycin-sensitive aminopeptidase-like prote
— OG7
LTRL590_270018200 ⚠
hypothetical protein
— OG7
LTRL590_360082800 ⚠
DNA-binding protein, putative
— OG7
LTRL590_310039600 ⚠
2-oxoglutarate dehydrogenase, e3 component, l
— OG7
LTRL590_310039500 ⚠
2-oxoglutarate dehydrogenase, e3 component, l
— OG7
LTRL590_110013100
3-methylcrotonoyl-CoA carboxylase beta subuni
— Both
LTRL590_310039700 ⚠
acetoin dehydrogenase e3 component-like prote
— Both
LTRL590_050006700
dihydrolipoamide branched chain transacylase,
— Both
LTRL590_160011200 ⚠
carbamoyl-phosphate synthase, putative
— Both
LTRL590_160011100 ⚠
carbamoyl-phosphate synthase, putative
— Both
LTRL590_290025000 ⚠
dihydrolipoamide dehydrogenase, putative
— Both
LTRL590_260007600 ⚠
aminopeptidase-like protein
— Both
LTRL590_210022200
2-oxoisovalerate dehydrogenase alpha subunit,
— Both
LTRL590_310045600 ⚠
methylcrotonoyl-coa carboxylase biotinylated
— Both
LTRL590_360040500
ATP synthase, putative
— Both
LTRL590_170012800 ⚠
guanosine monophosphate reductase
— OG6
LTRL590_190020000 ⚠
inosine-5'-monophosphate dehydrogenase
— Both
LTRL590_030006800
delta-1-pyrroline-5-carboxylate dehydrogenase
— Both
LTRL590_360039200 ⚠
bromodomain factor 2 protein, putative
— Both
LTRL590_130005800 ⚠
carboxypeptidase, putative
— Both
LTRL590_330033900 ⚠
carboxypeptidase, putative
— Both
LTRL590_360031600
tyrosine aminotransferase
— Both
LTRL590_140007000 ⚠
hypothetical protein
— Both
LTRL590_360075300 ⚠
carboxypeptidase, putative
— Both
LTRL590_060014000
dihydrofolate reductase-thymidylate synthase
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.