LTRL590_280036100

cytosolic malate dehydrogenase
Leishmania tropica L590 OG6: OG6_101066 OG7: OG7_0004490 37 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 37 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_340006500 ⚠
malate dehydrogenase, putative
— OG7
LTRL590_310039900 ⚠
glutamamyl carboxypeptidase (pseudogene), put
— Both
LTRL590_310040000 ⚠
hypothetical protein
— Both
LTRL590_310030300 ⚠
hypothetical protein
— OG6
LTRL590_310041800 ⚠
Peptidase family M20/M25/M40, putative
— Both
LTRL590_070008300 ⚠
acetylornithine deacetylase-like protein
— Both
LTRL590_070005300 ⚠
hypothetical protein
— Both
LTRL590_360080100
2,3-bisphosphoglycerate-independent phosphogl
— Both
LTRL590_190011900 ⚠
glycosomal malate dehydrogenase
— OG7
LTRL590_340006200 ⚠
malate dehydrogenase, putative
— OG7
LTRL590_170006900 ⚠
cystathionine beta-synthase
— Both
LTRL590_330037600 ⚠
D-alanyl-glycyl endopeptidase-like protein
— OG7
LTRL590_250031600 ⚠
glutathionylspermidine synthase, putative
— OG7
LTRL590_330037200 ⚠
D-alanyl-glycyl endopeptidase-like protein
— OG7
LTRL590_230010400 ⚠
trypanothione synthetase, putative
— OG7
LTRL590_310027400 ⚠
acetylornithine deacetylase-like protein
— OG7
LTRL590_070005400 ⚠
hypothetical protein, conserved
— OG7
LTRL590_000018400 ⚠
hypothetical protein
— OG7
LTRL590_290022500 ⚠
glutamamyl carboxypeptidase, putative
— OG7
LTRL590_290036100
inosine-adenosine-guanosine-nucleoside hydrol
— Both
LTRL590_220016900 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
LTRL590_100011500
nucleoside phosphorylase-like protein
— Both
LTRL590_040010700
spermidine synthase
— Both
LTRL590_270025900 ⚠
trypanothione synthetase, putative
— Both
LTRL590_140009200
threonine synthase, putative
— Both
LTRL590_260013000
aspartate--ammonia ligase, putative
— Both
LTRL590_300018800
pyridoxal kinase, putative
— Both
LTRL590_060010800
deoxyuridine triphosphatase, putative
— Both
LTRL590_270028000 ⚠
ribonucleoside-diphosphate reductase small ch
— Both
LTRL590_270027900 ⚠
hypothetical protein
— Both
LTRL590_270027700 ⚠
branched-chain amino acid aminotransferase, p
— Both
LTRL590_340006300 ⚠
lactate/malate dehydrogenase, NAD binding dom
— Both
LTRL590_340006400 ⚠
lactate/malate dehydrogenase, alpha/beta C-te
— Both
LTRL590_340006600 ⚠
malate dehydrogenase
— Both
LTRL590_240028300
transketolase
— Both
LTRL590_180009800
serine carboxypeptidase (CBP1), putative
— Both
LTRL590_360045800 ⚠
cysteine synthase
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.