LTRL590_320045000

3-hydroxyisobutyryl-coenzyme A hydrolase, putative
Leishmania tropica L590 OG6: OG6_102025 OG7: OG7_0000750 148 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 148 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_160013400 ⚠
Transaldolase, putative
— Both
LTRL590_160013100 ⚠
transaldolase, putative
— Both
LTRL590_130011200 ⚠
ubiquitin-like protein
— OG7
LTRL590_350051600 ⚠
CS domain containing protein, putative
— Both
LTRL590_180011900 ⚠
serine/threonine kinase-like protein, putativ
— Both
LTRL590_250019500 ⚠
NPL4 family, putative
— Both
LTRL590_010013300 ⚠
eukaryotic initiation factor 4a, putative
— Both
LTRL590_290020100 ⚠
carnitine/choline acetyltransferase, putative
— Both
LTRL590_180008200 ⚠
Dephospho-CoA kinase, putative
— Both
LTRL590_280017000 ⚠
WD domain, G-beta repeat, putative
— Both
LTRL590_320027800 ⚠
Cytidylyltransferase, putative
— Both
LTRL590_280017300 ⚠
electron-transfer-flavoprotein, alpha polypep
— Both
LTRL590_230025900 ⚠
alanine racemase, putative
— Both
LTRL590_220008300 ⚠
SEP domain containing protein, putative
— Both
LTRL590_300032300
RNA-binding protein, putative
— OG6
LTRL590_280019600 ⚠
haloacid dehalogenase-like hydrolase, putativ
— Both
LTRL590_240009000 ⚠
aspartate aminotransferase, putative
— Both
LTRL590_280020100 ⚠
haloacid dehalogenase-like hydrolase, putativ
— Both
LTRL590_350013100 ⚠
aspartate aminotransferase, putative
— Both
LTRL590_320015300 ⚠
Alpha/beta hydrolase family, putative
— Both
LTRL590_300021000 ⚠
epsilon-adaptin (pseudogene), putative
— Both
LTRL590_310006100 ⚠
ubiquitin hydrolase, putative
— Both
LTRL590_340043400 ⚠
phosphomannomutase-like protein
— Both
LTRL590_330015700 ⚠
nicotinate phosphoribosyltransferase, putativ
— Both
LTRL590_340039600 ⚠
amidinotransferase, putative
— Both
LTRL590_330037000 ⚠
transcription elongation factor-like protein
— Both
LTRL590_280028200 ⚠
tRNA threonylcarbamoyl adenosine modification
— Both
LTRL590_010006700
cyclophilin 12, putative
— OG6
LTRL590_030014700 ⚠
inorganic pyrophosphatase, putative
— Both
LTRL590_110007200 ⚠
acidocalcisomal pyrophosphatase
— Both
LTRL590_330011100 ⚠
hypothetical protein, conserved
— OG7
LTRL590_360046700 ⚠
nudix hydrolase-like protein
— OG7
LTRL590_310007700 ⚠
mitotic centromere-associated kinesin (MCAK),
— OG7
LTRL590_130006200 ⚠
MCAK-like kinesin, putative
— OG7
LTRL590_130021300 ⚠
MCAK-like kinesin, putative
— OG7
LTRL590_010005200 ⚠
MCAK-like kinesin, putative
— OG7
LTRL590_350008800 ⚠
ATP-dependent DEAD-box RNA helicase, putative
— OG7
LTRL590_210023600 ⚠
RNA helicase, putative
— OG7
LTRL590_280021900 ⚠
ATP-dependent RNA helicase FAL1, putative
— OG7
LTRL590_280019700 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
LTRL590_310042600 ⚠
aldehyde reductase, putative
— OG7
LTRL590_070005600 ⚠
alpha-adaptin-like protein
— OG7
LTRL590_340045800 ⚠
adaptor gamma-1 chain, putative
— OG7
LTRL590_300015000 ⚠
adenosine kinase-like protein
— OG7
LTRL590_300015100 ⚠
pfkB family carbohydrate kinase, putative
— OG7
LTRL590_220008200 ⚠
carnitine palmitoyltransferase-like protein
— OG7
LTRL590_190019800 ⚠
choline/Carnitine o-acyltransferase-like prot
— OG7
LTRL590_280019900 ⚠
hypothetical protein
— OG7
LTRL590_220008500 ⚠
Tetrahydrofolate dehydrogenase/cyclohydrolase
— OG7
LTRL590_250016600 ⚠
dehydrogenase-like protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.