LbrM.06.0630

Putative Phosphatase/Protein of unknown function DUF89, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_102304 OG7: OG7_0007072 24 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 24 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.21.1820
cytochrome b5-like Heme/Steroid binding domai
— OG6
LbrM.19.0140 ⚠
hypothetical protein, conserved
— OG7
LbrM.27.1560 ⚠
choline kinase, ethanolamine kinase, putative
— OG7
LbrM.01.0100
BSD domain containing protein, putative
— Both
LbrM.35.3430 ⚠
14-3-3 protein 1, putative
— OG6
LbrM.11.0040 ⚠
14-3-3 protein 2, putative
— OG6
LbrM.07.0100
pitrilysin-like metalloprotease, metallo-pept
— OG6
LbrM.04.0510
hypothetical protein
— OG6
LbrM.33.2550
glycosyl hydrolase-like protein
— OG6
LbrM.16.0010
anti-silencing protein a-like protein
— OG6
LbrM.21.1450
adenylate kinase, putative
— OG6
LbrM.25.1680
KIF-1 binding protein C terminal, putative
— OG6
LbrM.29.1290
hypothetical protein, conserved
— Both
LbrM.10.0060
thymidylate kinase-like protein
— OG6
LbrM.34.1390 ⚠
choline/ethanolamine kinase, putative
— Both
LbrM.32.1960
hypothetical protein, conserved
— Both
LbrM.33.2330
hypothetical protein, conserved
— Both
LbrM.30.1570 ⚠
RNA pseudouridylate synthase, putative
— Both
LbrM.30.1890 ⚠
RNA pseudouridylate synthase-like protein
— OG6
LbrM.24.2190
3-hydroxy-3-methylglutaryl-CoA synthase, puta
— Both
LbrM.16.0560
aspartate carbamoyltransferase, putative
— Both
LbrM.34.5050 ⚠
RNA pseudouridylate synthase, putative
— OG6
LbrM.32.0120
Qa-SNARE protein
— Both
LbrM.22.0730 ⚠
translation initiation factor SUI1, putative
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.