LbrM.08.0710

mitochondrial DNA polymerase beta
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_101198 OG7: OG7_0003693 14 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 14 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.19.1290 ⚠
WD domain, G-beta repeat, putative
— Both
LbrM.06.0350 ⚠
glutamine synthetase, putative
— Both
LbrM.27.2520 ⚠
GTP binding protein, putative
— Both
LbrM.23.0120 ⚠
GDP-mannose pyrophosphorylase
— Both
LbrM.31.2540 ⚠
hypothetical protein, conserved
— Both
LbrM.32.3400 ⚠
Serine hydrolase (FSH1)/50S ribosome-binding
— OG7
LbrM.27.1970 ⚠
GTP binding protein, putative
— OG7
LbrM.15.1230 ⚠
mitochondrial DNA topoisomerase II
— OG7
LbrM.17.0640 ⚠
Alpha/beta hydrolase family, putative
— OG7
LbrM.28.2480 ⚠
DNA topoisomerase ii
— OG7
LbrM.33.0010 ⚠
hypothetical protein, conserved
— OG7
LbrM.17.1260 ⚠
5'-3' exoribonuclease B, putative
— OG7
LbrM.35.1980 ⚠
5'-3' exoribonuclease D, putative
— OG7
LbrM.06.0240 ⚠
5'-3' exoribonuclease A, putative
— OG7
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.