LbrM.18.0170

serine/threonine protein phosphatase type 5, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_102598 OG7: OG7_0000696 17 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 17 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.34.4680
Hsp70 protein, putative
— OG6
LbrM.31.2810 ⚠
uridine kinase-like protein
— OG6
LbrM.32.0240
U2 small nuclear ribonucleoprotein 40K, putat
— OG6
LbrM.28.1010
oxidoreductase-like protein
— OG6
LbrM.22.1310 ⚠
fk506-binding protein 1-like protein
— OG6
LbrM.19.1790 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG6
LbrM.08.0470
WD domain, G-beta repeat, putative
— OG6
LbrM.18.0610
hypothetical protein, conserved
— OG6
LbrM.32.3160
cysteine peptidase, Clan CA, family C19, puta
— OG6
LbrM.29.2330
aspartyl aminopeptidase, putative
— OG6
LbrM.06.0550 ⚠
hypothetical protein, conserved
— OG6
LbrM.31.2760 ⚠
uridine kinase-like protein
— OG6
LbrM.20.1010 ⚠
uracil phosphoribosyltransferase, putative
— OG6
LbrM.20.6060
arginine N-methyltransferase-like protein
— OG6
LbrM.24.0010
pyruvate dehydrogenase (lipoamide) kinase, pu
— OG6
LbrM.11.0920
protein transport protein SEC31, putative
— OG6
LbrM.34.3550 ⚠
DNA repair protein RAD2, putative
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.