LbrM.35.1270

short chain 3-hydroxyacyl-CoA dehydrogenase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_101042 OG7: OG7_0000744 13 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 13 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.12.0810 ⚠
NADH:flavin oxidoreductase/NADH oxidase, puta
— Both
LbrM.12.0820 ⚠
n-ethylmaleimide reductase-like protein
— Both
LbrM.33.1020 ⚠
2,4-dienoyl-coa reductase fadh1, putative
— OG6
LbrM.32.0130
N-myristoyl transferase, putative
— Both
LbrM.23.0700 ⚠
ubiquitin-activating enzyme E1, putative
— Both
LbrM.23.0080
agmatinase-like protein
— OG6
LbrM.35.4070
glycyl tRNA synthetase, putative
— Both
LbrM.34.2970 ⚠
ubiquitin-activating enzyme E1, putative
— Both
LbrM.32.2490
heat shock protein Hsp20, putative
— Both
LbrM.23.0400
NADP-dependent alcohol dehydrogenase, putativ
— Both
LbrM.34.1400
arginase
— OG7
LbrM.20.5150 ⚠
1,2-Dihydroxy-3-keto-5-methylthiopentene diox
— OG7
LbrM.20.4060 ⚠
1,2-Dihydroxy-3-keto-5-methylthiopentene diox
— OG7
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.