LmxM.07.0480

Dynein heavy chain, N-terminal region 2, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_139865 OG7: OG7_0000699 50 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 50 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.34.3960 ⚠
protein kinase A catalytic subunit isoform 2
— OG6
LmxM.20.1120
phosphatidylinositol 3-kinase, putative
— OG6
LmxM.08_29.0810
hypothetical protein, conserved
— OG6
LmxM.34.1650
hypothetical protein, conserved
— OG6
LmxM.09.1220
AAA family ATPase, putative
— OG6
LmxM.22.1630
ccr4-not transcription complex subunit
— OG6
LmxM.08_29.1180
hypothetical protein, conserved
— OG6
LmxM.29.1600
hypothetical protein, conserved
— OG6
LmxM.31.0310
intraflagellar transport protein 140, putativ
— OG6
LmxM.32.1490
hypothetical protein, conserved
— OG6
LmxM.36.1000
intraflagellar transport protein 122, putativ
— OG6
LmxM.14.0880
hypothetical protein, conserved
— OG6
LmxM.23.0020
hypothetical protein, conserved
— OG6
LmxM.31.0250
hypothetical protein, conserved
— OG6
LmxM.29.0050
MATH domain containing protein, putative
— OG6
LmxM.29.2210
endosomal trafficking protein RME-8, putative
— OG6
LmxM.21.1330partial
RecF/RecN/SMC N terminal domain/SMC proteins
— OG6
LmxM.30.0130
hypothetical protein, unknown function
— OG6
LmxM.17.1140
WW domain containing protein, putative
— OG6
LmxM.11.0980
HIT zinc finger, putative
— OG6
LmxM.04.0550
Intraflagellar transport protein 139, putativ
— OG6
LmxM.05.0190
Fip1 motif/Zinc finger C-x8-C-x5-C-x3-H type
— OG6
LmxM.04.0690
axonemal dynein light chain, putative
— OG6
LmxM.03.0970
MORN repeat, putative
— OG6
LmxM.06.1160
hypothetical protein, conserved
— OG6
LmxM.30.3110
Flagellum attachment zone protein 14
— OG6
LmxM.05.0920
paraflagellar rod protein, putative
— OG6
LmxM.07.0280
HECT E3 ligase, putative
— OG6
LmxM.34.2700
hypothetical protein, conserved
— OG6
LmxM.21.1020
dynein arm light chain, putative
— OG6
LmxM.31.1340
cleavage and polyadenylation specificity fact
— OG6
LmxM.34.4010 ⚠
protein kinase A catalytic subunit isoform 1
— OG6
LmxM.32.2780
Concanavalin A-like lectin/glucanases superfa
— OG6
LmxM.24.0820
inositol polyphosphate phosphatase, putative
— OG6
LmxM.36.6340
HECT E3 ligase, putative
— OG6
LmxM.19.0680 ⚠
Flagellum attachment zone protein 7
— OG6
LmxM.18.1080 ⚠
protein kinase A catalytic subunit 3
— OG6
LmxM.29.0710
CDC16, putative
— OG6
LmxM.07.0120
Sec7 domain containing protein, putative
— OG6
LmxM.19.1010
WD domain, G-beta repeat, putative
— OG6
LmxM.17.0430
Kinetochore interacting protein 5, putative
— OG6
LmxM.23.1640
Galactose oxidase, central domain containing
— OG6
LmxM.29.0660
pdz domain containing protein, putative
— OG6
LmxM.27.2480
hypothetical protein, conserved, WD-repeat pr
— OG6
LmxM.21.1220
hypothetical protein, conserved
— OG6
LmxM.19.0690 ⚠
Flagellum attachment zone protein 7
— OG6
LmxM.26.1120
axonemal dynein light chain, putative
— OG6
LmxM.12.0610
TPR repeat, putative
— OG6
LmxM.32.1780
hypothetical protein, conserved
— OG6
LmxM.21.1670
hypothetical protein, conserved
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.