LmxM.08_29.2440

3'5'-cyclic nucleotide phosphodiesterase, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_124604 OG7: OG7_0000695 42 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 42 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.18.1580 ⚠
nonspecific nucleoside hydrolase
— OG7
LmxM.09.0530 ⚠
leucine-rich repeat protein, putative
— OG7
LmxM.08_29.0660 ⚠
flagellar radial spoke protein-like, putative
— OG7
LmxM.13.0430 ⚠
Flagellar radial spoke protein 4/6
— OG7
LmxM.19.1040 ⚠
phenylalanyl-tRNA synthetase, putative
— OG7
LmxM.27.1850 ⚠
paraflagellar rod protein 5, putative
— OG7
LmxM.08_29.1750 ⚠
paraflagellar rod protein 1D, putative
— OG7
LmxM.08_29.1760 ⚠
paraflagellar rod protein 1D, putative
— OG7
LmxM.15.0070 ⚠
hypothetical protein, conserved
— OG7
LmxM.09.0230 ⚠
ATP-dependent protease ATPase subunit HslU2
— OG7
LmxM.15.0090 ⚠
ATP-dependent protease ATPase subunit HslU1,
— OG7
LmxM.12.0200 ⚠
hypothetical protein, unknown function
— OG7
LmxM.14.0130 ⚠
nucleoside hydrolase-like protein
— OG7
LmxM.18.1090 ⚠
phosphodiesterase, putative
— OG7
LmxM.15.1481 ⚠
cAMP specific phosphodiesterase, putative
— OG7
LmxM.15.1480 ⚠
cAMP specific phosphodiesterase, putative
— OG7
LmxM.17.0950 ⚠
3'5'-cyclic nucleotide phosphodiesterase, put
— OG7
LmxM.08_29.2680 ⚠
hypothetical protein, conserved
— OG7
LmxM.25.1980 ⚠
hypothetical protein, conserved
— OG7
LmxM.13.1190 ⚠
adenylosuccinate synthetase, putative
— OG7
LmxM.33.0590 ⚠
nuclear cap binding complex subunit CBP110, p
— OG7
LmxM.24.1770 ⚠
inhibitor of cysteine peptidase
— OG7
LmxM.10.0800 ⚠
hypothetical protein, conserved
— OG7
LmxM.03.0970 ⚠
MORN repeat, putative
— OG7
LmxM.05.1080a ⚠
Phosphatidylinositol 4-phosphate 5-kinase, pu
— OG7
LmxM.05.1080 ⚠
Phosphatidylinositol 4-phosphate 5-kinase, pu
— OG7
LmxM.24.0910 ⚠
minchromosome maintenance (MCM) complex subun
— OG7
LmxM.26.2550 ⚠
hypothetical protein, conserved
— OG7
LmxM.31.2960 ⚠
minichromosome maintenance (MCM) complex subu
— OG7
LmxM.28.0850 ⚠
minichromosome maintenance (MCM) complex subu
— OG7
LmxM.28.2385 ⚠
DNA replication licensing factor, putative
— OG7
LmxM.34.4910 ⚠
DNA replication factor, putative
— OG7
LmxM.21.0910 ⚠
Aminoacyl-tRNA editing domain containing prot
— OG7
LmxM.32.2700 ⚠
minichromosome maintenance (MCM) complex subu
— OG7
LmxM.09.0250 ⚠
DNA replication licensing factor MCM4
— OG7
LmxM.05.0330 ⚠
DNA replication licensing factor, putative, m
— OG7
LmxM.34.0030 ⚠
pyruvate kinase, putative
— OG7
LmxM.34.0020 ⚠
pyruvate kinase
— OG7
LmxM.24.0020 ⚠
clathrin coat assembly protein, putative
— OG7
LmxM.08_29.0867 ⚠
guanine deaminase, putative
— OG7
LmxM.16.1430 ⚠
Paraflagellar rod protein 2
— OG7
LmxM.16.1425partial ⚠
paraflagellar rod protein 2C
— OG7
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.