TRSC58_02457

pre-mRNA-processing factor 8

Trypanosoma rangeli SC58 OG6: OG6_101765 OG7: OG7_0006744 68 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 68 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TRSC58_04833 ⚠ ATP-dependent RNA helicase	—	OG6 Tb927.5.2290 ↔ Tb927.9.11110 OG6 TCSYLVIO_005762 ↔ TCSYLVIO_008995 OG7 TCSYLVIO_005762 ↔ TCSYLVIO_008995 OG7 Tb927.5.2290 ↔ Tb927.9.11110	Both
TRSC58_01183 ⚠ RNA helicase	—	OG6 Tb927.5.2290 ↔ Tb927.9.11110 OG6 TCSYLVIO_005762 ↔ TCSYLVIO_008995 OG7 TCSYLVIO_005762 ↔ TCSYLVIO_008995 OG7 Tb927.5.2290 ↔ Tb927.9.11110	Both
TRSC58_00998 ⚠ RNA helicase	—	OG7 TCSYLVIO_005762 ↔ TCSYLVIO_008995 OG7 Tb927.5.2290 ↔ Tb927.9.11110	OG7
TRSC58_07010 ⚠ RNA helicase	—	OG7 TCSYLVIO_005762 ↔ TCSYLVIO_008995 OG7 Tb927.5.2290 ↔ Tb927.9.11110	OG7
TRSC58_05382 ⚠ RNA helicase	—	OG7 TCSYLVIO_005762 ↔ TCSYLVIO_008995 OG7 Tb927.5.2290 ↔ Tb927.9.11110	OG7
TRSC58_05988 ⚠ DNA polymerase theta (helicase domain only)	—	OG7 TCSYLVIO_005762 ↔ TCSYLVIO_008995 OG7 Tb927.5.2290 ↔ Tb927.9.11110	OG7
TRSC58_00955 proteasome regulatory ATPase subunit	—	OG6 TCSYLVIO_004751 ↔ TCSYLVIO_005762	OG6
TRSC58_06474 ⚠ activated protein kinase C receptor	—	OG7 Tb927.10.960 ↔ Tb927.9.11110	OG7
TRSC58_06654 hypothetical protein	—	OG6 TCSYLVIO_005364 ↔ TCSYLVIO_005762 OG7 TCSYLVIO_005364 ↔ TCSYLVIO_005762	Both
TRSC58_05508 small nuclear ribonucleoprotein SmD2	—	OG6 Tb927.2.5850 ↔ Tb927.9.11110 OG7 Tb927.2.5850 ↔ Tb927.9.11110	Both
TRSC58_05170 ⚠ small nuclear ribonucleoprotein Sm-F	—	OG6 Tb927.9.10250 ↔ Tb927.9.11110 OG7 Tb927.9.10250 ↔ Tb927.9.11110 OG7 Tb927.3.1780 ↔ Tb927.9.11110 OG7 Tb927.11.14310 ↔ Tb927.9.11110	Both
TRSC58_05743 hypothetical protein	—	OG6 Tb927.8.4790 ↔ Tb927.9.11110 OG7 Tb927.8.4790 ↔ Tb927.9.11110	Both
TRSC58_04093 ⚠ small nuclear ribonucleoprotein component	—	OG6 Tb927.11.15430 ↔ Tb927.9.11110 OG7 Tb927.11.15430 ↔ Tb927.9.11110	Both
TRSC58_02033 spliceosomal U5 snRNP-specific protein	—	OG6 Tb927.8.2560 ↔ Tb927.9.11110 OG7 Tb927.8.2560 ↔ Tb927.9.11110	Both
TRSC58_01471 ⚠ hypothetical protein	—	OG6 LdBPK_354000.1 ↔ LdBPK_366290.1 OG7 LdBPK_354000.1 ↔ LdBPK_366290.1	Both
TRSC58_00810 ⚠ hypothetical protein	—	OG6 LdBPK_354000.1 ↔ LdBPK_366290.1 OG7 LdBPK_354000.1 ↔ LdBPK_366290.1	Both
TRSC58_04920 40S ribosomal protein S10	—	OG6 LdBPK_354000.1 ↔ LdBPK_361050.1 OG7 LdBPK_354000.1 ↔ LdBPK_361050.1	Both
TRSC58_04540 hypothetical protein	—	OG6 Tb927.8.5180 ↔ Tb927.9.11110 OG7 Tb927.8.5180 ↔ Tb927.9.11110	Both
TRSC58_01856 proteasome regulatory non-ATPase subunit 3	—	OG6 TCSYLVIO_005523 ↔ TCSYLVIO_005762 OG7 TCSYLVIO_005523 ↔ TCSYLVIO_005762	Both
TRSC58_00348 proteasome regulatory non-ATPase subunit 6	—	OG6 TCSYLVIO_000894 ↔ TCSYLVIO_005762 OG7 TCSYLVIO_000894 ↔ TCSYLVIO_005762	Both
TRSC58_02439 ⚠ hypothetical protein	—	OG6 TCSYLVIO_002772 ↔ TCSYLVIO_005762 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_005762	Both
TRSC58_01972 hypothetical protein	—	OG6 Tb927.11.15690 ↔ Tb927.9.11110 OG7 Tb927.11.15690 ↔ Tb927.9.11110	Both
TRSC58_01648 hypothetical protein	—	OG6 TCSYLVIO_004088 ↔ TCSYLVIO_005762 OG7 TCSYLVIO_004088 ↔ TCSYLVIO_005762	Both
TRSC58_02169 ⚠ hypothetical protein	—	OG7 Tb927.10.960 ↔ Tb927.9.11110	OG7
TRSC58_02390 ⚠ acetyl-CoA carboxylase	—	OG6 TCSYLVIO_002772 ↔ TCSYLVIO_005762 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_005762	Both
TRSC58_03778 ⚠ U6 snRNA-associated Sm-like protein LSm6p	—	OG7 Tb927.9.10250 ↔ Tb927.9.11110 OG7 Tb927.3.1780 ↔ Tb927.9.11110 OG7 Tb927.11.14310 ↔ Tb927.9.11110	OG7
TRSC58_06578 ⚠ U6 snRNA-associated Sm-like protein LSm7	—	OG7 Tb927.9.10250 ↔ Tb927.9.11110 OG7 Tb927.3.1780 ↔ Tb927.9.11110 OG7 Tb927.11.14310 ↔ Tb927.9.11110	OG7
TRSC58_04189 ⚠ small nuclear ribonucleoprotein Sm-E	—	OG7 Tb927.9.10250 ↔ Tb927.9.11110 OG7 Tb927.3.1780 ↔ Tb927.9.11110 OG7 Tb927.11.14310 ↔ Tb927.9.11110	OG7
TRSC58_00608 ⚠ hypothetical protein	—	OG7 TCSYLVIO_005762 ↔ TCSYLVIO_007057	OG7
TRSC58_02713 ⚠ small nuclear ribonucleoprotein	—	OG7 Tb927.4.890 ↔ Tb927.9.11110	OG7
TRSC58_03088 ⚠ elongation factor 2	—	OG7 Tb927.11.15430 ↔ Tb927.9.11110	OG7
TRSC58_06347 ⚠ elongation factor 2	—	OG7 Tb927.11.15430 ↔ Tb927.9.11110	OG7
TRSC58_06854 ⚠ elongation factor 2	—	OG7 Tb927.11.15430 ↔ Tb927.9.11110	OG7
TRSC58_04517 ⚠ hypothetical protein	—	OG7 Tb927.11.15430 ↔ Tb927.9.11110	OG7
TRSC58_01553 ⚠ translation elongation factor EF-2	—	OG7 Tb927.11.15430 ↔ Tb927.9.11110	OG7
TRSC58_05168 proteasome regulatory non-ATPase subunit	—	OG6 TCSYLVIO_005762 ↔ TCSYLVIO_009688 OG7 TCSYLVIO_005762 ↔ TCSYLVIO_009688	Both
TRSC58_05490 hypothetical protein	—	OG6 TCSYLVIO_003465 ↔ TCSYLVIO_005762 OG7 TCSYLVIO_003465 ↔ TCSYLVIO_005762	Both
TRSC58_02244 proteasome regulatory ATPase subunit 1	—	OG6 TCSYLVIO_001254 ↔ TCSYLVIO_005762	OG6
TRSC58_00414 hypothetical protein	—	OG6 TCSYLVIO_005762 ↔ TCSYLVIO_010962 OG7 TCSYLVIO_005762 ↔ TCSYLVIO_010962	Both
TRSC58_06330 ⚠ 26S proteasome regulatory subunit N1	—	OG6 TCSYLVIO_005762 ↔ TCSYLVIO_010720 OG7 TCSYLVIO_005762 ↔ TCSYLVIO_010720	Both
TRSC58_05928 hypothetical protein	—	OG6 TCSYLVIO_005762 ↔ TCSYLVIO_009030	OG6
TRSC58_02424 protein kinase	—	OG6 TCSYLVIO_005762 ↔ TCSYLVIO_007056	OG6
TRSC58_00459 proteasome regulatory ATPase subunit 3	—	OG6 TCSYLVIO_005762 ↔ TCSYLVIO_006982	OG6
TRSC58_03376 proteasome regulatory non-ATPase subunit 5	—	OG6 TCSYLVIO_005762 ↔ TCSYLVIO_007986 OG7 TCSYLVIO_005762 ↔ TCSYLVIO_007986	Both
TRSC58_02253 ⚠ small nuclear ribonucleoprotein Sm-G	—	OG6 Tb927.11.14310 ↔ Tb927.9.11110 OG7 Tb927.9.10250 ↔ Tb927.9.11110 OG7 Tb927.3.1780 ↔ Tb927.9.11110 OG7 Tb927.11.14310 ↔ Tb927.9.11110	Both
TRSC58_03435 ⚠ hypothetical protein	—	OG6 TCSYLVIO_005762 ↔ TCSYLVIO_007057 OG7 TCSYLVIO_005762 ↔ TCSYLVIO_007057	Both
TRSC58_04413 hypothetical protein	—	OG6 TCSYLVIO_005762 ↔ TCSYLVIO_005994 OG7 TCSYLVIO_005762 ↔ TCSYLVIO_005994	Both
TRSC58_04807 proteasome regulatory non-ATPase subunit 8	—	OG6 TCSYLVIO_005762 ↔ TCSYLVIO_006095 OG7 TCSYLVIO_005762 ↔ TCSYLVIO_006095	Both
TRSC58_04318 ⚠ 26S proteasome regulatory non-ATPase subunit	—	OG6 TCSYLVIO_005762 ↔ TCSYLVIO_010720 OG7 TCSYLVIO_005762 ↔ TCSYLVIO_010720	Both
TRSC58_07068 ⚠ 26S proteasome regulatory subunit N1	—	OG6 TCSYLVIO_005762 ↔ TCSYLVIO_010720 OG7 TCSYLVIO_005762 ↔ TCSYLVIO_010720	Both

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