TcCLB.506221.80

NAD+ synthase, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_100679 OG7: OG7_0004572 20 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 20 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.510565.11 ⚠
tyrosine aminotransferase, putative (fragment
— Both
TcCLB.511181.50 ⚠
mitochondrial processing peptidase, beta subu
— OG7
TcCLB.510751.10 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
TcCLB.508535.50 ⚠
tyrosine aminotransferase
— OG7
TcCLB.506239.40
U-box domain containing protein, putative
— Both
TcCLB.506635.80
Hydroxymethylglutaryl-CoA lyase, mitochondria
— Both
TcCLB.510295.50
Mitogen-activated protein kinase 6
— OG6
TcCLB.503747.10 ⚠
glutamine aminotransferase, putative (fragmen
— Both
TcCLB.503887.30
hypothetical protein, conserved
— Both
TcCLB.508537.5 ⚠
tyrosine aminotransferase, putative (fragment
— Both
TcCLB.503881.10
kynureninase, putative
— Both
TcCLB.506251.100 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
TcCLB.507047.110
otubain cysteine peptidase, Clan CA, family C
— Both
TcCLB.508169.50
hypothetical protein, conserved
— Both
TcCLB.504427.200 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
TcCLB.505965.50
phosphonopyruvate decarboxylase, putative
— Both
TcCLB.509169.30
NUDIX hydrolase domain-like domain-containing
— Both
TcCLB.509151.130
deoxyuridine triphosphatase, putative, dUTP d
— Both
TcCLB.511585.80 ⚠
mitochondrial-processing peptidase subunit be
— Both
TcCLB.511439.100
p-nitrophenylphosphatase, putative
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.