TvY486_0200690

ATP-dependent Clp protease subunit, heat shock protein 78 (HSP78), putative, serine peptidase, putative
Trypanosoma vivax Y486 OG6: OG6_100223 OG7: OG7_0002479 171 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 171 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_0603280 ⚠
heat shock 70 kDa protein, mitochondrial prec
— Both
TvY486_1004580 ⚠
elongation factor 2, putative, (fragment)
— OG7
TvY486_1004590 ⚠
elongation factor 2, putative, (fragment)
— OG7
TvY486_1109880 ⚠
hypothetical protein, conserved
— OG7
TvY486_0301540 ⚠
translation elongation factor EF-2, putative
— Both
TvY486_0805700 ⚠
Galactose oxidase, central domain/Kelch motif
— OG7
TvY486_1109870 ⚠
Galactose oxidase, central domain containing
— OG7
TvY486_1008420 ⚠
Galactose oxidase, central domain containing
— OG7
TvY486_0100220 ⚠
kelch domain-containing protein
— OG7
TvY486_1005840 ⚠
Galactose oxidase, central domain containing
— OG7
TvY486_0503360 ⚠
Galactose oxidase, central domain/Domain of u
— OG7
TvY486_1116220 ⚠
U5 small nuclear ribonucleoprotein component,
— Both
TvY486_1112460 ⚠
Galactose oxidase, central domain containing
— OG7
TvY486_0603230 ⚠
heat shock 70 kDa protein, mitochondrial prec
— Both
TvY486_0702940 ⚠
Galactose oxidase, central domain containing
— Both
TvY486_0603220 ⚠
heat shock 70 kDa protein, mitochondrial prec
— Both
TvY486_1004930 ⚠
dihydrouridine synthase domain protein, putat
— OG7
TvY486_1014910 ⚠
ABC transporter, putative
— OG7
TvY486_0021890 ⚠
hypothetical protein (fragment)
— OG7
TvY486_0402970 ⚠
tRNA-dihydrouridine synthase 4, putative
— OG7
TvY486_1010490 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
TvY486_0806820 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
TvY486_1009570 ⚠
ubiquitin-protein ligase, putative
— OG7
TvY486_0025980 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
TvY486_0706230 ⚠
BTB/POZ domain/Regulator of chromosome conden
— OG7
TvY486_0400480 ⚠
ubiquitin-protein ligase, putative
— OG7
TvY486_1106950 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
TvY486_1111190 ⚠
regulator of chromosome condensation 1-like p
— OG7
TvY486_1101490 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— Both
TvY486_0200450 ⚠
casein kinase II, alpha chain, putative
— OG6
TvY486_1109660 ⚠
Replication factor A protein 1
— Both
TvY486_0802730 ⚠
Beta-lactamase superfamily domain containing
— Both
TvY486_0703040 ⚠
Beta-lactamase superfamily domain containing
— Both
TvY486_1010390 ⚠
iron-containing hydrogenase, putative
— Both
TvY486_1100300 ⚠
conserved protein
— Both
TvY486_1116170 ⚠
Importin subunit beta-4, putative
— OG7
TvY486_0802530 ⚠
hypothetical protein, conserved
— OG7
TvY486_1115100 ⚠
small nuclear ribonucleoprotein Sm-G
— OG7
TvY486_0033520 ⚠
ubiquitin hydrolase, putative
— OG7
TvY486_1107120 ⚠
regulator of chromatin condensation, putative
— OG7
TvY486_0041460 ⚠
chromatin binding protein, putative
— OG7
TvY486_1010370 ⚠
hypothetical protein, conserved
— Both
TvY486_0019440 ⚠
p22 protein precursor, putative
— OG7
TvY486_0603050 ⚠
hypothetical protein, conserved
— OG7
TvY486_1003160 ⚠
ABC transporter protein, putative
— OG7
TvY486_0503440 ⚠
u6 snrna-associated sm-like protein
— OG7
TvY486_0703360 ⚠
p22 protein precursor, putative
— OG7
TvY486_0907260 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TvY486_0901110 ⚠
u6 snrna-associated sm-like protein, Sm- like
— OG7
TvY486_1115120 ⚠
ubiquitin transferase, (fragment)
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.