TvY486_0600250

ATP-dependent DEAD/H RNA helicase, putative
Trypanosoma vivax Y486 OG6: OG6_126543 OG7: OG7_0000698 69 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 69 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_0039290 ⚠
hypothetical protein
— OG6
TvY486_1008260
ubiquitin-protein ligase, putative, (fragment
— OG6
TvY486_0033220 ⚠
microtubule-associated protein, putative, (fr
— OG6
TvY486_0905720 ⚠
Putative death-receptor fusion protein (DUF24
— OG6
TvY486_0201490
hypothetical protein, conserved (fragment)
— OG6
TvY486_1114750
kinesin, putative, (fragment)
— OG6
TvY486_0002640 ⚠
microtubule-associated protein, putative, (fr
— OG6
TvY486_1015130
hypothetical protein, conserved
— OG6
TvY486_0600830
hypothetical protein, conserved
— OG6
TvY486_1008310 ⚠
Phosphatidylinositol 3-kinase tor1
— OG6
TvY486_0004990 ⚠
kinesin, putative (fragment)
— OG6
TvY486_0700600
dynein arm light chain, axonemal, putative
— OG6
TvY486_1008880
hypothetical protein, conserved
— OG6
TvY486_1006950
hypothetical protein, conserved
— OG6
TvY486_0032990
hypothetical protein, conserved (fragment)
— OG6
TvY486_0301240
General negative regulator of transcription s
— OG6
TvY486_1009010
Cyclin 12, L-type
— OG6
TvY486_0901370
Ring finger domain/Zn-finger in ubiquitin-hyd
— OG6
TvY486_0905810 ⚠
60S ribosomal subunit protein L31, putative
— OG6
TvY486_0702340
proteasome regulatory ATPase subunit 1, (frag
— OG6
TvY486_1114230
AAA ATPase, putative, (fragment), AAA family
— OG6
TvY486_1002730
hypothetical protein, conserved
— OG6
TvY486_0905800 ⚠
60S ribosomal subunit protein, putative
— OG6
TvY486_0302440
serine/threonine-protein kinase Nek, putative
— OG6
TvY486_0907250
casein kinase II, putative
— OG6
TvY486_0604140
protein mkt1, putative
— OG6
TvY486_0400120 ⚠
Phosphatidylinositol 3-kinase tor2
— OG6
TvY486_0902290
protein phosphatase 2A regulatory subunit, pu
— OG6
TvY486_1102540 ⚠
Unc104-like kinesin, putative, (fragment)
— OG6
TvY486_0300490
Putative intraflagellar transport protein A1
— OG6
TvY486_0304320
kinesin, putative
— OG6
TvY486_1011810
hypothetical protein, conserved
— OG6
TvY486_1013910
intraflagellar transport protein 140, putativ
— OG6
TvY486_1112380
hypothetical protein, conserved
— OG6
TvY486_1115420
Microtubule-binding protein MIP-T3, putative
— OG6
TvY486_0801230
Sec7 domain containing protein, putative
— OG6
TvY486_0903040
DENN (AEX-3) domain containing protein, putat
— OG6
TvY486_0801040
ubiquitin-protein ligase, putative, (fragemnt
— OG6
TvY486_1006180 ⚠
5'-3' exoribonuclease D, putative
— OG6
TvY486_0704970 ⚠
5'-3' exoribonuclease A, putative
— OG6
TvY486_1015000
WD domain, G-beta repeat, putative
— OG6
TvY486_1113910
hypothetical protein, conserved
— OG6
TvY486_1007310 ⚠
fibrillarin, putative
— OG6
TvY486_1014170 ⚠
fibrillarin, putative
— OG6
TvY486_0803950
hypothetical protein, conserved
— OG6
TvY486_0706690
paraflagellar rod protein, putative
— OG6
TvY486_0601490
AMP-binding enzyme, putative
— OG6
TvY486_0902180
glutamate dehydrogenase, putative
— OG6
TvY486_1104640
hypothetical protein, conserved
— OG6
TvY486_1000730
structural maintenance of chromosome
— OG6
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.