TvY486_0905720

Putative death-receptor fusion protein (DUF2428), putative
Trypanosoma vivax Y486 OG6: OG6_146318 OG7: OG7_0006293 96 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 96 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_1002230 ⚠
Peptidase C19, ubiquitin carboxyl-terminal hy
— OG7
TvY486_1110160 ⚠
replication factor C, subunit 4, putative
— OG7
TvY486_0905840 ⚠
replication factor C, subunit 3, putative
— OG7
TvY486_1110130 ⚠
replication factor C, subunit 4, putative
— OG7
TvY486_0706520 ⚠
ATPase family associated with various cellula
— OG7
TvY486_0044030 ⚠
replication factor C, subunit 4, putative
— OG7
TvY486_1105870 ⚠
replication factor C, subunit 1, putative
— OG7
TvY486_0023700 ⚠
replication factor C, subunit 4, putative
— OG7
TvY486_1007860 ⚠
replication factor C subunit 3, putative
— OG7
TvY486_0705460 ⚠
hypothetical protein, conserved
— OG7
TvY486_0803050 ⚠
JAB1/Mov34/MPN/PAD-1 ubiquitin protease, puta
— OG7
TvY486_0906960 ⚠
hypothetical protein, conserved
— OG7
TvY486_0603360 ⚠
replication factor C, subunit 2, putative
— OG7
TvY486_0602180 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
TvY486_1105470 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TvY486_0604140 ⚠
protein mkt1, putative
— Both
TvY486_0400150 ⚠
coatomer alpha subunit, putative
— Both
TvY486_1006950 ⚠
hypothetical protein, conserved
— Both
TvY486_1008880 ⚠
hypothetical protein, conserved
— Both
TvY486_1009010 ⚠
Cyclin 12, L-type
— Both
TvY486_0300630 ⚠
DNA-directed RNA polymerase I subunit RPB10,
— Both
TvY486_0600250 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG6
TvY486_0802860 ⚠
Inositol hexakisphosphate, putative
— Both
TvY486_0901370 ⚠
Ring finger domain/Zn-finger in ubiquitin-hyd
— Both
TvY486_0402400 ⚠
eukaryotic translation initiation factor 2-al
— OG7
TvY486_0704910 ⚠
hypothetical protein, conserved
— OG7
TvY486_1114870 ⚠
cyclin 9, putative
— OG7
TvY486_1008470 ⚠
hypothetical protein, conserved
— OG7
TvY486_1112780 ⚠
hypothetical protein, conserved
— OG7
TvY486_1012260 ⚠
Protein of unknown function (DUF3648), putati
— OG7
TvY486_1004470 ⚠
leucine carboxyl methyltransferase, putative
— OG7
TvY486_1114210 ⚠
hypothetical protein, conserved
— OG7
TvY486_1114200 ⚠
hypothetical protein, conserved
— OG7
TvY486_0400380 ⚠
hypothetical protein, conserved
— OG7
TvY486_0907260 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TvY486_0404200 ⚠
hypothetical protein, conserved
— OG7
TvY486_1117770 ⚠
chaperonin alpha subunit, putative
— +4 more Both
TvY486_1005980 ⚠
proteasome subunit alpha type-1, putative
— OG7
TvY486_0028820 ⚠
hypothetical protein, conserved in T.vivax
— OG7
TvY486_1107320 ⚠
proteasome alpha 7 subunit, putative, (fragme
— OG7
TvY486_1103330 ⚠
T-complex protein 1, zeta subunit, putative
— +3 more OG7
TvY486_0020590 ⚠
hypothetical protein, conserved in T.vivax
— OG7
TvY486_0904170 ⚠
20S proteasome subunit, proteasome alpha 1 su
— OG7
TvY486_0033450 ⚠
hypothetical protein, conserved in T. vivax (
— OG7
TvY486_1000230 ⚠
proteasome alpha 2 subunit, putative
— OG7
TvY486_0704500 ⚠
proteasome alpha 3 subunit, putative
— OG7
TvY486_0300190 ⚠
proteasome alpha 7 subunit, (fragment)
— OG7
TvY486_0100870 ⚠
Replication Factor C Subunit 1-related protei
— OG7
TvY486_1105170 ⚠
hypothetical protein, conserved
— Both
TvY486_0004990 ⚠
kinesin, putative (fragment)
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.