TvY486_0803980

Eukaryotic translation initiation factor 4 gamma 5
Trypanosoma vivax Y486 OG6: OG6_139892 OG7: OG7_0037732 73 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 73 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_1115330
G5-interacting protein, putative
— Both
TvY486_0007550 ⚠
Mitochondrial outer membrane protein porin, p
— Both
TvY486_0600290
ccr4-not transcription complex subunit 2
— Both
TvY486_1001510
CCR4-NOT transcription complex subunit 1
— Both
TvY486_0901370
Ring finger domain/Zn-finger in ubiquitin-hyd
— Both
TvY486_0502190
Beta-lactamase superfamily domain containing
— Both
TvY486_0200172 ⚠
cyclophilin-type peptidyl-prolyl cis-trans is
— OG6
TvY486_0801500 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG6
TvY486_1100730 ⚠
cyclophilin a, putative
— OG6
TvY486_0200476 ⚠
Mitochondrial outer membrane protein porin, p
— Both
TvY486_0006360 ⚠
hypothetical protein, conserved (fragment)
— Both
TvY486_0901740
hypothetical protein, conserved
— Both
TvY486_0807180 ⚠
'Cold-shock' DNA-binding domain containing pr
— Both
TvY486_0014510 ⚠
hypothetical protein, conserved
— Both
TvY486_1108630 ⚠
mitochondrial RNA binding protein, putative
— Both
TvY486_0902600
cAMP-specific phosphodiesterase, putative
— Both
TvY486_0903040
DENN (AEX-3) domain containing protein, putat
— Both
TvY486_1113910
hypothetical protein, conserved
— Both
TvY486_1006030 ⚠
universal minicircle sequence binding protein
— Both
TvY486_0602180 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
TvY486_0704910
hypothetical protein, conserved
— OG7
TvY486_1002230 ⚠
Peptidase C19, ubiquitin carboxyl-terminal hy
— OG7
TvY486_1012260
Protein of unknown function (DUF3648), putati
— OG7
TvY486_1114870 ⚠
cyclin 9, putative
— OG7
TvY486_1008470
hypothetical protein, conserved
— OG7
TvY486_0900580
hypothetical protein, conserved
— OG7
TvY486_0400380 ⚠
hypothetical protein, conserved
— OG7
TvY486_0907260 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TvY486_0603710 ⚠
glyceraldehyde 3-phosphate dehydrogenase, put
— Both
TvY486_0706450
Kinetochore interacting protein 5, putative
— OG7
TvY486_1105470 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TvY486_0904290 ⚠
glyceraldehyde-3-phosphate dehydrogenase, put
— OG7
TvY486_1114210 ⚠
hypothetical protein, conserved
— OG7
TvY486_1114200 ⚠
hypothetical protein, conserved
— OG7
TvY486_0701510
Eukaryotic translation initiation factor 4E t
— Both
TvY486_1008080
Ribosomal protein L1p/L10e family, putative
— Both
TvY486_1107070 ⚠
hypothetical protein, conserved (fragment)
— Both
TvY486_0902290
protein phosphatase 2A regulatory subunit, pu
— Both
TvY486_0010350 ⚠
ubiquitin hydrolase, putative
— Both
TvY486_1010810
hypothetical protein, conserved (fragment)
— Both
TvY486_0039290 ⚠
hypothetical protein
— Both
TvY486_0004990 ⚠
kinesin, putative (fragment)
— OG6
TvY486_1008880
hypothetical protein, conserved
— Both
TvY486_1006950
hypothetical protein, conserved
— Both
TvY486_1013600
nuclear segregation protein, putative
— Both
TvY486_0033520 ⚠
ubiquitin hydrolase, putative
— Both
TvY486_1014170 ⚠
fibrillarin, putative
— Both
TvY486_0201934 ⚠
hypothetical protein, conserved
— Both
TvY486_1009010 ⚠
Cyclin 12, L-type
— Both
TvY486_0600250
ATP-dependent DEAD/H RNA helicase, putative
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.