TvY486_0902600

cAMP-specific phosphodiesterase, putative
Trypanosoma vivax Y486 OG6: OG6_146459 OG7: OG7_0042785 68 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 68 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_0400380 ⚠
hypothetical protein, conserved
— Both
TvY486_0907260 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TvY486_0025980 ⚠
cysteine peptidase, Clan CA, family C19, puta
— Both
TvY486_0033520 ⚠
ubiquitin hydrolase, putative
— Both
TvY486_0906080 ⚠
ubiquitin-activating enzyme E1, putative
— Both
TvY486_0901370
Ring finger domain/Zn-finger in ubiquitin-hyd
— Both
TvY486_0403150
Carnosine N-methyltransferase, putative
— Both
TvY486_1003320
protein kinase, putative
— OG6
TvY486_0706820
hypothetical protein, conserved (fragment)
— Both
TvY486_0603470
TPR domain protein, conserved, putative
— OG6
TvY486_0604130
T-complex protein 11, putative
— Both
TvY486_0601670
co-chaperone, putative
— Both
TvY486_0802170 ⚠
ubiquitin-activating enzyme E1, putative
— Both
TvY486_0501890
TPR repeat, putative
— Both
TvY486_0501200
replication Factor A 28 kDa subunit, putative
— Both
TvY486_0304190
ubiquitin carboxyl-terminal hydrolase, putati
— Both
TvY486_1002730
hypothetical protein, conserved
— Both
TvY486_0902180
glutamate dehydrogenase, putative
— Both
TvY486_0302440
serine/threonine-protein kinase Nek, putative
— OG6
TvY486_1112480
Mitochondrial import receptor subunit ATOM69,
— Both
TvY486_0803980
Eukaryotic translation initiation factor 4 ga
— Both
TvY486_1105470 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TvY486_0706450
Kinetochore interacting protein 5, putative
— OG7
TvY486_0602180 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
TvY486_1114200 ⚠
hypothetical protein, conserved
— OG7
TvY486_0900580
hypothetical protein, conserved
— OG7
TvY486_1008470
hypothetical protein, conserved
— OG7
TvY486_0704910
hypothetical protein, conserved
— OG7
TvY486_1114870 ⚠
cyclin 9, putative
— OG7
TvY486_1114210 ⚠
hypothetical protein, conserved
— OG7
TvY486_1012260
Protein of unknown function (DUF3648), putati
— OG7
TvY486_1002230 ⚠
Peptidase C19, ubiquitin carboxyl-terminal hy
— OG7
TvY486_0304710 ⚠
centaurin beta 5, ADP-ribosylation factor GTP
— OG7
TvY486_0009630 ⚠
ADP-ribosylation factor GTPase activating pro
— OG7
TvY486_1109700 ⚠
centaurin beta 5, ADP-ribosylation factor GTP
— OG7
TvY486_0201934 ⚠
hypothetical protein, conserved
— Both
TvY486_0004990 ⚠
kinesin, putative (fragment)
— OG6
TvY486_0502190
Beta-lactamase superfamily domain containing
— Both
TvY486_1008880
hypothetical protein, conserved
— Both
TvY486_1006950
hypothetical protein, conserved
— Both
TvY486_1013600
nuclear segregation protein, putative
— Both
TvY486_0903040
DENN (AEX-3) domain containing protein, putat
— Both
TvY486_1113910
hypothetical protein, conserved
— Both
TvY486_0902290
protein phosphatase 2A regulatory subunit, pu
— Both
TvY486_0039290 ⚠
hypothetical protein
— Both
TvY486_0600250
ATP-dependent DEAD/H RNA helicase, putative
— OG6
TvY486_1009010 ⚠
Cyclin 12, L-type
— Both
TvY486_0300590
GIY-YIG catalytic domain containing protein,
— Both
TvY486_1115200 ⚠
ADP-ribosylation factor GTPase activating pro
— Both
TvY486_1108560
ribonucleoside-diphosphate reductase large ch
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.