TvY486_1108560

ribonucleoside-diphosphate reductase large chain, putative
Trypanosoma vivax Y486 OG6: OG6_100448 OG7: OG7_0004229 105 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 105 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_1007930 ⚠
hypothetical protein, conserved
— OG7
TvY486_1100750 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— Both
TvY486_0905750
6-phosphogluconate dehydrogenase, decarboxyla
— Both
TvY486_0601410
N-acetyltransferase B complex (NatB) non cata
— Both
TvY486_0503260
aspartate carbamoyltransferase, putative
— Both
TvY486_0706760
methylthioadenosine phosphorylase, putative
— Both
TvY486_0802010
3-ketoacyl-CoA thiolase, putative, (fragment)
— Both
TvY486_0803090 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— Both
TvY486_0300010
N-acetyltransferase complex ARD1 subunit, put
— Both
TvY486_0706820
hypothetical protein, conserved (fragment)
— Both
TvY486_1111970
translation initiation factor 2 subunit, puta
— Both
TvY486_1010050
hypothetical protein, conserved
— Both
TvY486_0604050
hypothetical protein, conserved
— Both
TvY486_1115810
hypothetical protein, conserved
— Both
TvY486_1103000
hypothetical protein, conserved
— Both
TvY486_0802120
5-methyltetrahydropteroyltriglutamate-homocys
— Both
TvY486_0304116
leucine-rich repeat-containing protein
— Both
TvY486_0021270 ⚠
protein kinase, putative
— Both
TvY486_0806100 ⚠
protein kinase, putative
— Both
TvY486_1109070 ⚠
ribonuclease II-like protein, putative, (frag
— Both
TvY486_0803650
hypothetical protein, conserved
— Both
TvY486_0100630
conserved protein, unknown function
— Both
TvY486_1108060 ⚠
rrp44p homologue, putative
— OG7
TvY486_0902820 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
TvY486_0603330 ⚠
leucyl/phenylalanyl-tRNA protein transferase,
— OG7
TvY486_0301460 ⚠
hypothetical protein, conserved
— OG7
TvY486_0302770 ⚠
hypothetical protein, conserved
— OG7
TvY486_0907260 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
TvY486_1010600 ⚠
heat shock protein 83, putative, (fragment)
— OG7
TvY486_1109700 ⚠
centaurin beta 5, ADP-ribosylation factor GTP
— OG7
TvY486_0009630 ⚠
ADP-ribosylation factor GTPase activating pro
— OG7
TvY486_0023660 ⚠
lipophosphoglycan biosynthetic protein, putat
— OG7
TvY486_0303270 ⚠
heat shock protein, putative
— OG7
TvY486_0601610 ⚠
NUDC-like protein, putative, nuclear movement
— OG7
TvY486_0304710 ⚠
centaurin beta 5, ADP-ribosylation factor GTP
— OG7
TvY486_0025980 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
TvY486_0501830 ⚠
NOL1/NOP2/sun family, putative
— OG7
TvY486_1106950 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
TvY486_1012630 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
TvY486_0302990 ⚠
heat shock protein 90, putative
— OG7
TvY486_0604290 ⚠
protein kinase, putative, serine/arginine-ric
— OG7
TvY486_1011130 ⚠
hypothetical protein, conserved
— OG7
TvY486_1004200 ⚠
hypothetical protein, conserved
— OG7
TvY486_0906500 ⚠
hypothetical protein, conserved
— OG7
TvY486_0703520 ⚠
tyrosyl-tRNA synthetase, putative
— OG7
TvY486_1107310 ⚠
protein kinase, putative
— OG7
TvY486_1107290 ⚠
serine/threonine protein kinase, putative
— OG7
TvY486_1010590 ⚠
heat shock protein 83, (fragment)
— OG7
TvY486_1010610 ⚠
heat shock protein 83
— OG7
TvY486_0033520 ⚠
ubiquitin hydrolase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.