C4B63_18g288

heat shock 70 kDa protein, mitochondrial precursor
Trypanosoma cruzi Dm28c 2018 OG6: OG6_100423 OG7: OG7_0000776 73 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 73 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_63g68 ⚠
ATP-dependent protease binding subunit(fragme
— Both
C4B63_9g299 ⚠
ATP-dependent Clp protease subunit, heat shoc
— Both
C4B63_9g471 ⚠
ATP-dependent protease binding subunit(fragme
— Both
C4B63_9g416 ⚠
ATP-dependent Clp protease subunit, heat shoc
— Both
C4B63_34g114 ⚠
ATP-dependent Clp protease subunit, heat shoc
— Both
C4B63_2g687 ⚠
conserved hypothetical protein
— Both
C4B63_8g2646c ⚠
10 kDa heat shock protein
— Both
C4B63_49g120 ⚠
Acyl-CoA-binding domain-containing protein 4
— OG6
C4B63_23g1250c ⚠
heat shock protein 20
— Both
C4B63_113g63 ⚠
conserved hypothetical protein
— Both
C4B63_279g12 ⚠
beta tubulin
— OG6
C4B63_333g13 ⚠
alpha tubulin
— OG6
C4B63_51g127 ⚠
beta tubulin
— OG6
C4B63_333g15 ⚠
alpha tubulin
— OG6
C4B63_333g18 ⚠
alpha tubulin
— OG6
C4B63_333g14 ⚠
beta tubulin
— OG6
C4B63_333g17 ⚠
alpha tubulin
— OG6
C4B63_333g21 ⚠
beta tubulin
— OG6
C4B63_279g11 ⚠
alpha tubulin
— OG6
C4B63_333g12 ⚠
beta tubulin
— OG6
C4B63_333g19 ⚠
alpha tubulin
— OG6
C4B63_22g172 ⚠
beta tubulin
— OG6
C4B63_271g80c ⚠
U6 snRNA-associated Sm-like protein LSm7p
— OG7
C4B63_95g32 ⚠
conserved hypothetical protein
— OG7
C4B63_83g29 ⚠
ATP-dependent protease ATPase subunit HslU1
— OG7
C4B63_13g162 ⚠
cap guanine-N7 methyltransferase
— OG7
C4B63_95g34 ⚠
mitochondrial processing peptidase alpha subu
— OG7
C4B63_58g112 ⚠
mitochondrial processing peptidase alpha subu
— OG7
C4B63_17g179 ⚠
Importin subunit beta-3
— OG7
C4B63_11g283c ⚠
U6 snRNA-associated Sm-like protein LSm8
— OG7
C4B63_43g1065c ⚠
U6 snRNA-associated Sm-like protein LSm7p
— OG7
C4B63_87g33 ⚠
conserved hypothetical protein
— Both
C4B63_69g174c ⚠
U6 snRNA-associated Sm-like protein LSm6p
— OG7
C4B63_144g102c ⚠
U6 snRNA-associated Sm-like protein LSm6p
— OG7
C4B63_19g113 ⚠
Translation machinery-associated protein 22
— Both
C4B63_87g32 ⚠
conserved hypothetical protein
— Both
C4B63_222g21 ⚠
alpha tubulin
— OG6
C4B63_8g2652c ⚠
10 kDa heat shock protein
— Both
C4B63_8g2656c ⚠
10 kDa heat shock protein
— Both
C4B63_28g407c ⚠
Archaic Translocase of outer membrane 14 kDa
— Both
C4B63_20g61 ⚠
conserved hypothetical protein
— Both
C4B63_295g15 ⚠
nucleosome assembly protein-like protein
— Both
C4B63_304g13 ⚠
nucleosome assembly protein
— Both
C4B63_4g454 ⚠
nucleosome assembly protein
— Both
C4B63_26g252 ⚠
nucleosome assembly protein-like protein
— Both
C4B63_142g8 ⚠
methyltransferase
— Both
C4B63_20g226 ⚠
Probable importin subunit beta-4
— Both
C4B63_27g180 ⚠
ATP-dependent protease ATPase subunit HslU2
— Both
C4B63_85g40 ⚠
conserved hypothetical protein
— Both
C4B63_2g553 ⚠
Programmed cell death 6-interacting protein
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.