C4B63_63g68

ATP-dependent protease binding subunit(fragment)
Trypanosoma cruzi Dm28c 2018 OG6: OG6_100223 OG7: OG7_0002479 192 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 192 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_18g287 ⚠
heat shock 70 kDa protein, mitochondrial prec
— Both
C4B63_49g120 ⚠
Acyl-CoA-binding domain-containing protein 4
— OG6
C4B63_9g523 ⚠
U5 small nuclear ribonucleoprotein component
— Both
C4B63_11g18 ⚠
translation elongation factor EF-2
— Both
C4B63_11g17 ⚠
translation elongation factor EF-2
— Both
C4B63_18g288 ⚠
heat shock 70 kDa protein, mitochondrial prec
— Both
C4B63_18g293 ⚠
heat shock 70 kDa protein, mitochondrial prec
— Both
C4B63_13g152 ⚠
elongation factor 2
— OG7
C4B63_13g157 ⚠
elongation factor 2
— OG7
C4B63_13g153 ⚠
elongation factor 2
— OG7
C4B63_13g156 ⚠
elongation factor 2
— OG7
C4B63_13g155 ⚠
elongation factor 2
— OG7
C4B63_13g154 ⚠
elongation factor 2
— OG7
C4B63_113g58 ⚠
hydrogenase
— Both
C4B63_49g54 ⚠
p22 protein precursor (Mitochondrial glycopro
— OG7
C4B63_47g107 ⚠
ABC transporter
— OG7
C4B63_17g98 ⚠
E3 ubiquitin-protein ligase UPL3
— OG7
C4B63_144g102c ⚠
U6 snRNA-associated Sm-like protein LSm6p
— OG7
C4B63_61g23 ⚠
tRNA-dihydrouridine synthase 3
— OG7
C4B63_18g319 ⚠
Internalin-A
— OG7
C4B63_26g231 ⚠
ubiquitin hydrolase(fragment)
— OG7
C4B63_14g171 ⚠
ubiquitin-protein ligase
— OG7
C4B63_2g4 ⚠
ubiquitin hydrolase
— OG7
C4B63_206g11 ⚠
ABC transporter
— OG7
C4B63_113g49 ⚠
metallo-peptidase, Clan MC, Family M14
— OG7
C4B63_26g232 ⚠
ubiquitin hydrolase(fragment)
— OG7
C4B63_40g50 ⚠
metallo-peptidase, Clan MC, Family M14
— OG7
C4B63_16g95 ⚠
conserved hypothetical protein
— OG7
C4B63_17g179 ⚠
Importin subunit beta-3
— OG7
C4B63_6g262 ⚠
MRP protein
— OG6
C4B63_142g8 ⚠
methyltransferase
— Both
C4B63_16g331 ⚠
ubiquitin-activating enzyme E1
— Both
C4B63_2g786 ⚠
ubiquitin-activating enzyme E1
— Both
C4B63_160g33 ⚠
ubiquitin-activating enzyme E1
— Both
C4B63_30g290 ⚠
mercaptopyruvate sulfurtransferase
— Both
C4B63_22g79 ⚠
Tubulin/FtsZ family
— Both
C4B63_85g40 ⚠
conserved hypothetical protein
— Both
C4B63_4g250 ⚠
Zinc finger, C3HC4 type (RING finger) contain
— OG6
C4B63_46g49 ⚠
conserved hypothetical protein
— Both
C4B63_52g42 ⚠
glutathione synthetase
— Both
C4B63_101g36 ⚠
inositol-3-phosphate synthase
— Both
C4B63_355g19 ⚠
inositol-3-phosphate synthase(fragment)
— Both
C4B63_34g313 ⚠
casein kinase II, alpha chain
— OG6
C4B63_243g12 ⚠
Vacuolar protein sorting-associated protein V
— Both
C4B63_49g130 ⚠
Putative hydrolase C777.06c
— Both
C4B63_49g131 ⚠
conserved hypothetical protein
— Both
C4B63_16g122 ⚠
Beta-lactamase superfamily domain containing
— Both
C4B63_6g411 ⚠
Replication factor A 51 kDa subunit
— Both
C4B63_330g2 ⚠
MRP protein
— OG6
C4B63_79g85 ⚠
nucleotide-binding protein
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.