C4B63_20g44

conserved hypothetical protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_171517 OG7: OG7_0063832 20 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 20 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_1g39 ⚠
paraflagellar rod component
— Both
C4B63_35g113 ⚠
conserved hypothetical protein
— OG7
C4B63_4g478 ⚠
DNA-directed RNA polymerases I and III subuni
— OG7
C4B63_89g44 ⚠
proteasome beta-1 subunit
— OG7
C4B63_2g692 ⚠
proteasome beta-1 subunit
— OG7
C4B63_7g234
Signal recognition particle subunit SRP68
— Both
C4B63_8g50
mitochondrial RNA binding complex 1 subunit
— Both
C4B63_20g197 ⚠
exosome-associated protein 2
— Both
C4B63_49g170 ⚠
ribosomal RNA processing protein 45
— Both
C4B63_19g76
conserved hypothetical protein
— Both
C4B63_42g107
conserved hypothetical protein
— Both
C4B63_10g507 ⚠
DNA-directed RNA polymerases I and III subuni
— Both
C4B63_235g17 ⚠
paraflagellar rod component
— Both
C4B63_31g60
delta-adaptin
— Both
C4B63_48g131 ⚠
proteasome subunit beta type-5
— Both
C4B63_27g168 ⚠
flagellar pocket cytoskeletal protein bilbo1
— Both
C4B63_232g18
exosome complex exonuclease
— Both
C4B63_87g42
conserved hypothetical protein
— Both
C4B63_85g59
pre-mRNA processing factor 3 (PRP3)
— Both
C4B63_32g250
Peptidyl-prolyl cis-trans isomerase H
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.