C4B63_85g59

pre-mRNA processing factor 3 (PRP3)
Trypanosoma cruzi Dm28c 2018 OG6: OG6_157627 OG7: OG7_0043643 63 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 63 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_271g80c ⚠
U6 snRNA-associated Sm-like protein LSm7p
— OG7
C4B63_9g2075c
small nuclear ribonucleoprotein SmD2
— Both
C4B63_9g523 ⚠
U5 small nuclear ribonucleoprotein component
— Both
C4B63_55g176
Putative snoRNA binding domain containing pro
— Both
C4B63_9g462
U5 snRNP-associated 102 kDa protein
— Both
C4B63_137g47 ⚠
receptor for activated C kinase 1
— OG7
C4B63_137g46 ⚠
receptor for activated C kinase 1
— OG7
C4B63_18g20 ⚠
Protein will die slowly
— OG7
C4B63_137g48 ⚠
receptor for activated C kinase 1
— OG7
C4B63_137g44 ⚠
receptor for activated C kinase 1
— OG7
C4B63_6g320 ⚠
receptor for activated C kinase 1
— OG7
C4B63_6g321 ⚠
receptor for activated C kinase 1
— OG7
C4B63_42g593c ⚠
small nuclear ribonucleoprotein Sm-E
— OG7
C4B63_69g174c ⚠
U6 snRNA-associated Sm-like protein LSm6p
— OG7
C4B63_137g45 ⚠
receptor for activated C kinase 1
— OG7
C4B63_144g102c ⚠
U6 snRNA-associated Sm-like protein LSm6p
— OG7
C4B63_2g1123c ⚠
small nuclear ribonucleoprotein Sm-F
— Both
C4B63_43g1065c ⚠
U6 snRNA-associated Sm-like protein LSm7p
— OG7
C4B63_43g154 ⚠
TRAF3-interacting protein 1
— OG7
C4B63_17g180c
U6 snRNA-associated Sm-like protein LSm4
— OG7
C4B63_13g152 ⚠
elongation factor 2
— OG7
C4B63_13g157 ⚠
elongation factor 2
— OG7
C4B63_13g153 ⚠
elongation factor 2
— OG7
C4B63_11g18 ⚠
translation elongation factor EF-2
— OG7
C4B63_11g17 ⚠
translation elongation factor EF-2
— OG7
C4B63_13g156 ⚠
elongation factor 2
— OG7
C4B63_13g155 ⚠
elongation factor 2
— OG7
C4B63_13g154 ⚠
elongation factor 2
— OG7
C4B63_2g692 ⚠
proteasome beta-1 subunit
— OG7
C4B63_89g44 ⚠
proteasome beta-1 subunit
— OG7
C4B63_4g478 ⚠
DNA-directed RNA polymerases I and III subuni
— OG7
C4B63_35g113 ⚠
conserved hypothetical protein
— OG7
C4B63_10g507 ⚠
DNA-directed RNA polymerases I and III subuni
— Both
C4B63_133g31
U5 snRNP-specific 40 kDa protein
— Both
C4B63_43g214 ⚠
U4/U6 small nuclear ribonuclear protein
— Both
C4B63_8g545
conserved hypothetical protein
— Both
C4B63_17g45
kinesin
— OG6
C4B63_17g276 ⚠
TRAF3-interacting protein 1
— Both
C4B63_58g144
Cilia- and flagella-associated protein 70
— Both
C4B63_42g174
conserved hypothetical protein
— Both
C4B63_32g250
Peptidyl-prolyl cis-trans isomerase H
— Both
C4B63_87g42
conserved hypothetical protein
— Both
C4B63_232g18
exosome complex exonuclease
— Both
C4B63_27g168 ⚠
flagellar pocket cytoskeletal protein bilbo1
— Both
C4B63_48g131 ⚠
proteasome subunit beta type-5
— Both
C4B63_31g60
delta-adaptin
— Both
C4B63_7g234
Signal recognition particle subunit SRP68
— Both
C4B63_235g17 ⚠
paraflagellar rod component
— Both
C4B63_42g107
conserved hypothetical protein
— Both
C4B63_1g39 ⚠
paraflagellar rod component
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.