LAEL147_000250300

guanosine monophosphate reductase
Leishmania aethiopica L147 OG6: OG6_100534 OG7: OG7_0002928 62 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 62 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000768100 ⚠
Eukaryotic rRNA processing protein EBP2, puta
— Both
LAEL147_000093300 ⚠
hypothetical protein, conserved
— OG6
LAEL147_000270400 ⚠
Prolyl-tRNA synthetase, C-terminal, putative
— OG6
LAEL147_000270500 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— OG6
LAEL147_000270300 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— OG6
LAEL147_000652100 ⚠
Prefoldin subunit, putative
— OG6
LAEL147_000466000 ⚠
cysteine desulfurase, putative
— Both
LAEL147_000156100 ⚠
PUB domain containing protein, putative
— OG6
LAEL147_000238100 ⚠
EMG1/NEP1 methyltransferase, putative
— Both
LAEL147_000229900 ⚠
carbamoyl-phosphate synthase, putative
— OG6
LAEL147_000749800 ⚠
2-oxoisovalerate dehydrogenase beta subunit,
— OG6
LAEL147_000762400 ⚠
hypothetical protein, conserved
— Both
LAEL147_000412300 ⚠
ATPase beta subunit, putative
— OG6
LAEL147_000534700 ⚠
dihydrolipoamide dehydrogenase, putative
— OG6
LAEL147_000833700 ⚠
glyceraldehyde 3-phosphate dehydrogenase, cyt
— OG6
LAEL147_000578000 ⚠
glyceraldehyde 3-phosphate dehydrogenase, gly
— OG6
LAEL147_000413100 ⚠
hypothetical protein, conserved
— OG6
LAEL147_000578100 ⚠
glyceraldehyde 3-phosphate dehydrogenase, gly
— OG6
LAEL147_000552800 ⚠
ribosome biogenesis regulatory protein (RRS1)
— Both
LAEL147_000760300 ⚠
KRI1-like family/KRI1-like family C-terminal,
— Both
LAEL147_000614700 ⚠
acetoin dehydrogenase e3 component-like prote
— OG6
LAEL147_000152600 ⚠
3-methylcrotonoyl-CoA carboxylase beta subuni
— OG6
LAEL147_000426100 ⚠
brix domain containing-like protein
— Both
LAEL147_000155800 ⚠
Leucine Rich repeat, putative
— OG6
LAEL147_000031000 ⚠
Soluble NSF attachment protein, SNAP, putativ
— OG6
LAEL147_000105200 ⚠
WD domain, G-beta repeat, putative
— OG6
LAEL147_000045200 ⚠
peter pan protein, putative
— Both
LAEL147_000268400 ⚠
5-oxoprolinase, putative
— OG6
LAEL147_000629000 ⚠
RNA binding protein, putative
— Both
LAEL147_000463300 ⚠
hypothetical protein, conserved
— Both
LAEL147_000478200 ⚠
EMG1/NEP1 methyltransferase, putative
— OG7
LAEL147_000502300 ⚠
p21-C-terminal region-binding protein, putati
— OG6
LAEL147_000153000 ⚠
aminopeptidase, putative
— OG6
LAEL147_000463500 ⚠
hypothetical protein, conserved
— Both
LAEL147_000310100 ⚠
ribosome biogenesis protein, putative
— Both
LAEL147_000034700 ⚠
Nop14-like family, putative
— OG6
LAEL147_000767100 ⚠
casein kinase II, putative
— OG6
LAEL147_000609400 ⚠
ARM-like helical domain-containing protein
— OG6
LAEL147_000565000 ⚠
hypothetical protein, conserved
— OG6
LAEL147_000552200 ⚠
hypothetical protein, conserved
— OG6
LAEL147_000412600 ⚠
WD domain, G-beta repeat, putative
— Both
LAEL147_000783400 ⚠
RNA-binding protein, putative
— OG6
LAEL147_000334900 ⚠
transcription factor-like protein
— OG6
LAEL147_000601900 ⚠
Leucine-rich repeat - CC (cysteine-containing
— OG6
LAEL147_000322200 ⚠
HEAT-like repeat, putative
— OG6
LAEL147_000725600 ⚠
asparaginyl-tRNA synthetase, putative
— OG6
LAEL147_000540600 ⚠
aspartyl aminopeptidase, putative
— OG6
LAEL147_000152900 ⚠
aminopeptidase, putative
— OG6
LAEL147_000433900 ⚠
hypothetical protein, conserved
— OG6
LAEL147_000589300 ⚠
CRAL/TRIO domain containing protein, putative
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.