LAEL147_000387500

translation initiation factor IF-2, putative
Leishmania aethiopica L147 OG6: OG6_147564 OG7: OG7_0005015 90 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 90 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000618500 ⚠
Component of IIS longevity pathway SMK-1, put
— OG7
LAEL147_000542400 ⚠
NOL1/NOP2/sun family, putative
— OG7
LAEL147_000194900 ⚠
N-terminal conserved domain of Nudc./CS domai
— OG7
LAEL147_000081900 ⚠
Acyl-CoA dehydrogenase, C-terminal domain con
— OG7
LAEL147_000014500 ⚠
calreticulin, putative
— OG7
LAEL147_000875300 ⚠
disgorgin, putative
— OG7
LAEL147_000579900 ⚠
valyl-tRNA synthetase, putative
— OG7
LAEL147_000049200 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LAEL147_000515000 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
LAEL147_000553700 ⚠
nuclear movement protein, putative
— OG7
LAEL147_000668100 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
LAEL147_000435600 ⚠
Glucosidase II beta subunit-like/Glucosidase
— OG7
LAEL147_000458000 ⚠
nucleoporin, putative
— OG7
LAEL147_000574000 ⚠
formate--tetrahydrofolate ligase
— OG7
LAEL147_000571000 ⚠
SET domain containing protein, putative
— OG7
LAEL147_000875400 ⚠
rab-like GTPase activating protein, putative
— OG7
LAEL147_000422300 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000235500 ⚠
tyrosyl or methionyl-tRNA synthetase-like pro
— OG7
LAEL147_000507400 ⚠
serine hydroxymethyltransferase (SHMT-L)
— OG7
LAEL147_000797800 ⚠
Cysteine-rich motif following a subset of SET
— OG7
LAEL147_000670900 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000082600 ⚠
glucosamine-fructose-6-phosphate aminotransfe
— OG7
LAEL147_000831700 ⚠
NOL1/NOP2/sun family, putative
— OG7
LAEL147_000338800 ⚠
Putative tRNA binding domain containing prote
— OG7
LAEL147_000687100 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000485900 ⚠
DIS3-like exonuclease, putative
— OG7
LAEL147_000269100 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
LAEL147_000305200 ⚠
Pre-mRNA-splicing factor 38, putative
— OG7
LAEL147_000283400 ⚠
ABC transport system ATP-binding protein, put
— OG7
LAEL147_000259100 ⚠
alpha glucosidase II subunit, putative
— OG7
LAEL147_000854200 ⚠
glycosyl hydrolase-like protein
— OG7
LAEL147_000081800 ⚠
acyl-coenzyme a dehydrogenase, putative
— OG7
LAEL147_000067600 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000511100 ⚠
Uncharacterized ACR, COG1678, putative
— OG7
LAEL147_000037400 ⚠
ATP-binding cassette protein subfamily F, mem
— OG7
LAEL147_000834900 ⚠
dipeptidyl-peptidase 8-like serine peptidase,
— OG7
LAEL147_000552900 ⚠
histidyl-tRNA synthetase, putative
— OG7
LAEL147_000753500 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000778100 ⚠
acyl-CoA dehydrogenase, putative
— OG7
LAEL147_000401300 ⚠
cleavage and polyadenylation specificity fact
— OG7
LAEL147_000491200 ⚠
endonuclease/exonuclease/phosphatase-like pro
— OG7
LAEL147_000681100 ⚠
protein kinase, putative
— OG7
LAEL147_000425700 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000715800 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LAEL147_000724400 ⚠
Endonuclease/Exonuclease/phosphatase family,
— OG7
LAEL147_000870300 ⚠
isoleucyl-tRNA synthetase, putative
— OG7
LAEL147_000011200 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000536300 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000354300 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
LAEL147_000205600 ⚠
serine hydroxymethyltransferase (SHMT-L)
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.