LINF_280014500

ribonucleoside-diphosphate reductase large chain - putative
Leishmania infantum JPCM5 OG6: OG6_100448 OG7: OG7_0004229 106 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 106 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_260006500 ⚠
nuclear lim interactor-interacting factor-lik
— OG7
LINF_050012000
Sperm-tail PG-rich repeat - putative
— Both
LINF_230013100 ⚠
ubiquitin-activating enzyme E1 - putative
— Both
LINF_350035900 ⚠
ubiquitin-activating enzyme E1 - putative
— Both
LINF_110012700
anion-transporting ATPase-like protein
— Both
LINF_100008300
isocitrate dehydrogenase [NADP] - mitochondri
— Both
LINF_350038800
6-phosphogluconate dehydrogenase - decarboxyl
— Both
LINF_160010500
aspartate carbamoyltransferase - putative
— Both
LINF_050013500
methylthioadenosine phosphorylase - putative
— Both
LINF_230014600 ⚠
3-ketoacyl-CoA thiolase - putative
— Both
LINF_250005100
n-terminal acetyltransferase complex ard1 sub
— Both
LINF_300010300
N-acetyltransferase B complex (NatB) non cata
— Both
LINF_300038900
hypothetical protein - conserved
— Both
LINF_330029400
hypothetical protein - conserved
— Both
LINF_330017600
PSP1 C-terminal conserved region containing p
— Both
LINF_330014800 ⚠
NLI interacting factor-like phosphatase - put
— Both
LINF_310005000
5-methyltetrahydropteroyltriglutamate-homocys
— Both
LINF_360057300
paraflagellar rod component - putative
— Both
LINF_290029800
leucine-rich repeat-containing protein
— Both
LINF_320023600
hypothetical protein - conserved
— Both
LINF_240023300 ⚠
calcium/calmodulin-dependent protein kinase -
— Both
LINF_100015100 ⚠
hypothetical protein - conserved
— Both
LINF_280007900 ⚠
DIS3-like exonuclease - putative
— Both
LINF_280009200 ⚠
rrp44p homologue - putative
— OG7
LINF_040008400 ⚠
mitochondrial exoribonuclease DSS-1 - putativ
— OG7
LINF_350026800 ⚠
adenine aminohydrolase
— OG7
LINF_300031000 ⚠
hypothetical protein - conserved
— OG7
LINF_150020800 ⚠
ubiquitin hydrolase - putative
— OG7
LINF_150007700 ⚠
sterol carrier protein - putative
— OG7
LINF_180016500 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
LINF_130012000 ⚠
Putative GTPase activating protein for Arf -
— OG7
LINF_290008300 ⚠
Putative GTPase activating protein for Arf -
— OG7
LINF_340028800 ⚠
asparaginyl-tRNA synthetase - putative
— OG7
LINF_280024000 ⚠
Putative GTPase activating protein for Arf -
— OG7
LINF_320021500 ⚠
Putative GTPase activating protein for Arf -
— OG7
LINF_300012100 ⚠
nuclear movement protein - putative
— OG7
LINF_110012000 ⚠
aminopeptidase - putative
— OG7
LINF_300012600 ⚠
heat shock protein grpe
— OG7
LINF_350022300 ⚠
ubiquitin hydrolase - putative
— OG7
LINF_110011900 ⚠
aminopeptidase - putative
— OG7
LINF_290031700 ⚠
NLI interacting factor-like phosphatase - put
— OG7
LINF_320006000 ⚠
NLI interacting factor-like phosphatase - put
— OG7
LINF_350040600 ⚠
NLI interacting factor-like phosphatase - put
— OG7
LINF_360079600 ⚠
nuclear lim interactor-interacting factor - p
— OG7
LINF_350007000 ⚠
NLI interacting factor-like phosphatase - put
— OG7
LINF_250027200 ⚠
NLI interacting factor-like phosphatase - put
— OG7
LINF_350031400 ⚠
TFIIF-stimulated CTD phosphatase - putative
— OG7
LINF_140020100 ⚠
tyrosyl-tRNA synthetase - putative
— OG7
LINF_310017600 ⚠
amidohydrolase - putative
— OG7
LINF_300041600 ⚠
serine/threonine-protein kinase - putative
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.