LINF_100008300

isocitrate dehydrogenase [NADP] - mitochondrial precursor - putative
Leishmania infantum JPCM5 OG6: OG6_100639 OG7: OG7_0004251 179 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 179 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_010005200 ⚠
Kinesin-13
— OG7
LINF_180007900 ⚠
Dephospho-CoA kinase - putative
— Both
LINF_360010600 ⚠
protein phosphatase 2C-like protein
— OG6
LINF_280017100
electron-transfer-flavoprotein - alpha polype
— Both
LINF_220008200
SEP domain containing protein - putative
— Both
LINF_230025500
alanine racemase - putative
— Both
LINF_320022600 ⚠
protein phosphatase 2C - putative
— OG6
LINF_270030600 ⚠
protein phosphatase-like protein
— OG6
LINF_340025000
pyroglutamyl-peptidase I (C15 family)
— Both
LINF_100008500 ⚠
protein transport protein SEC23 - putative
— Both
LINF_200022700
CHORD - putative
— Both
LINF_320014700
Alpha/beta hydrolase family - putative
— Both
LINF_340030900
protein phosphatase 2C-like protein
— OG6
LINF_340045400
phosphomannomutase-like protein
— Both
LINF_270032100 ⚠
TPR-repeat protein - putative
— OG6
LINF_360005700 ⚠
stress-inducible protein STI1 homolog
— OG6
LINF_200011400 ⚠
hypothetical protein - conserved
— Both
LINF_360053800 ⚠
mitochondrial intermediate peptidase - putati
— Both
LINF_210005600 ⚠
BAR domain containing protein - putative
— Both
LINF_360011200 ⚠
Elongation factor G1 - mitochondrial - putati
— Both
LINF_320005800
N-myristoyl transferase - putative
— Both
LINF_320036800 ⚠
nucleoside diphosphate kinase b
— Both
LINF_280027300
Telomere recombination/Putative GTP-binding c
— Both
LINF_320036700 ⚠
nucleoside diphosphate kinase b
— Both
LINF_160011100
dihydroorotase - putative
— Both
LINF_300026200
alcohol dehydrogenase - putative
— Both
LINF_310006400
ubiquitin carboxyl-terminal hydrolase - putat
— Both
LINF_010007100
cyclophilin 12 - putative
— OG6
LINF_350019800 ⚠
choline/ethanolamine kinase - putative
— Both
LINF_330017000
nicotinate phosphoribosyltransferase - putati
— Both
LINF_330037400 ⚠
transcription elongation factor-like protein
— Both
LINF_270013300 ⚠
UBA/TS-N domain containing protein - putative
— Both
LINF_030014200 ⚠
inorganic pyrophosphatase - putative
— Both
LINF_110007000 ⚠
acidocalcisomal pyrophosphatase
— Both
LINF_200011000
cytidine triphosphate synthase - putative
— Both
LINF_080009900
hypothetical protein - conserved
— Both
LINF_250023500
DnaJ domain containing protein - putative
— Both
LINF_180015200
UDP-glucose pyrophosphorylase
— Both
LINF_360045400
NUDIX hydrolase 3 - putative
— Both
LINF_120005100
PITH domain-containing protein
— Both
LINF_210006900 ⚠
serine/threonine-protein kinase-like protein
— OG7
LINF_360014700 ⚠
SNF1-related protein kinases - putative
— OG7
LINF_330025600 ⚠
protein kinase - putative
— OG7
LINF_220014000 ⚠
serine/threonine protein kinase sos2 - putati
— OG7
LINF_280026600 ⚠
protein kinase - putative
— OG7
LINF_270033860 ⚠
hypothetical protein (non-ATG)
— OG7
LINF_300014400 ⚠
adenosine kinase - putative
— OG7
LINF_300014500 ⚠
adenosine kinase-like protein
— OG7
LINF_260020700 ⚠
thimet oligopeptidase - putative
— OG7
LINF_340043400 ⚠
adenosine kinase-like protein
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.