LPAL13_040006000

cAMP-specific phosphodiesterase, putative
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_146459 OG7: OG7_0042785 90 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 90 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_340021800 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_150017600 ⚠
ubiquitin hydrolase, putative
— Both
LPAL13_200044400 ⚠
ubiquitin hydrolase, putative
— Both
LPAL13_110010800
anion-transporting ATPase-like protein
— Both
LPAL13_240011800 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_000009400
protein farnesyltransferase alpha subunit, pu
— Both
LPAL13_150011800
hypothetical protein, conserved
— Both
LPAL13_300013000 ⚠
co-chaperone GrpE, putative
— Both
LPAL13_010008900 ⚠
Ring finger domain/Zn-finger in ubiquitin-hyd
— Both
LPAL13_280029300
hypothetical protein, conserved
— Both
LPAL13_200014800
N2227-like protein, putative
— Both
LPAL13_030008200
protein kinase, putative
— Both
LPAL13_350082100 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LPAL13_050011300
Sperm-tail PG-rich repeat, putative
— Both
LPAL13_300031400
small glutamine-rich tetratricopeptide repeat
— OG6
LPAL13_300038800
T-complex protein 11, putative
— Both
LPAL13_230014200 ⚠
ubiquitin-activating enzyme E1, putative
— Both
LPAL13_340035400 ⚠
ubiquitin-activating enzyme E1, putative
— Both
LPAL13_170018300
TPR repeat, putative
— Both
LPAL13_150008100
replication Factor A 28 kDa subunit, putative
— Both
LPAL13_290025400
ubiquitin hydrolase, putative
— Both
LPAL13_000025800
translation-associated element 2, putative
— Both
LPAL13_210015200
Aminoacyl-tRNA editing domain containing prot
— Both
LPAL13_350015700
hypothetical protein, conserved
— Both
LPAL13_290015700 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LPAL13_290008400 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LPAL13_130010200 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LPAL13_320022200 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LPAL13_280025300 ⚠
Putative GTPase activating protein for Arf, p
— OG7
LPAL13_300013100 ⚠
heat shock protein grpe
— OG7
LPAL13_200035800 ⚠
Zn-finger in ubiquitin-hydrolases and other p
— OG7
LPAL13_030010800
hypothetical protein, conserved
— OG7
LPAL13_170007300 ⚠
WD domain, G-beta repeat, putative
— OG7
LPAL13_320022000 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LPAL13_190006700 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
LPAL13_000033700
Beta-lactamase superfamily domain containing
— Both
LPAL13_350055100 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LPAL13_000050300 ⚠
Temperature dependent protein affecting M2 ds
— OG7
LPAL13_300017500 ⚠
ubiquitin hydrolase, putative
— OG7
LPAL13_090017200 ⚠
hypothetical protein, conserved
— OG7
LPAL13_340014500 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
LPAL13_210008900 ⚠
Peptidase C19, ubiquitin carboxyl-terminal hy
— OG7
LPAL13_100006100 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LPAL13_340056200 ⚠
PSP1 C-terminal conserved region containing p
— OG7
LPAL13_330038900 ⚠
hypothetical protein, conserved
— OG7
LPAL13_320013200 ⚠
cyclin 9, putative
— OG7
LPAL13_330010300
hypothetical protein, conserved
— Both
LPAL13_340038400
Putative death-receptor fusion protein (DUF24
— Both
LPAL13_040011600
DENN (AEX-3) domain containing protein, putat
— Both
LPAL13_320020100
G5-interacting protein, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.