LPAL13_200062400

RNasePH-like protein
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_146086 OG7: OG7_0043575 43 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 43 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_040007100
exosome complex exonuclease RRP40, putative
— Both
LPAL13_350049200 ⚠
hypothetical protein
— OG7
LPAL13_280035900 ⚠
heat-shock protein hsp70, putative
— Both
LPAL13_250011200 ⚠
RNA polymerase I second largest subunit, puta
— Both
LPAL13_250018500
hypothetical protein, conserved
— Both
LPAL13_070009300
RAVE protein 1 C terminal, putative
— Both
LPAL13_070012900 ⚠
topoisomerase-related function protein-like p
— Both
LPAL13_030008200
protein kinase, putative
— Both
LPAL13_300038900 ⚠
protein mkt1, putative
— OG7
LPAL13_280006400 ⚠
DNA-direcetd RNA polymerase II, subunit 9, pu
— OG7
LPAL13_190012200 ⚠
DNA-directed RNA polymerase III subunit C11,
— OG7
LPAL13_200013200 ⚠
elongation factor 1-beta
— Both
LPAL13_040010900 ⚠
Nucleotidyltransferase domain/Cid1 family pol
— OG7
LPAL13_350049100 ⚠
Nucleotidyltransferase domain containing prot
— OG7
LPAL13_260009700 ⚠
DNA polymerase sigma-like protein
— OG7
LPAL13_200048300 ⚠
DNA-directed RNA polymerase polypeptide, puta
— OG7
LPAL13_180016300 ⚠
heat shock protein 110, putative
— OG7
LPAL13_340053700 ⚠
Hsp70 protein, putative
— OG7
LPAL13_010010200 ⚠
HSP70-like protein
— OG7
LPAL13_260013400 ⚠
heat shock 70 protein-like protein
— OG7
LPAL13_310006600 ⚠
DNA-directed RNA polymerase polypeptide, puta
— OG7
LPAL13_260009600 ⚠
Conserved hypothetical ATP binding protein, p
— OG7
LPAL13_280036000 ⚠
heat-shock protein hsp70, putative
— Both
LPAL13_260010600
hypothetical protein, conserved
— Both
LPAL13_310018100
Protein of unknown function (DUF3638)/Protein
— Both
LPAL13_350062300
glycosyl hydrolase, putative
— Both
LPAL13_300016700
RNA-binding protein, putative
— OG6
LPAL13_220018500
hypothetical protein, conserved
— Both
LPAL13_000050300 ⚠
Temperature dependent protein affecting M2 ds
— Both
LPAL13_350050700 ⚠
DNA-directed RNA polymerase I subunit, putati
— Both
LPAL13_340007800
3-hydroxyacyl-CoA dehydrogenase, C-terminal d
— Both
LPAL13_350020400 ⚠
translation elongation factor 1-beta, putativ
— Both
LPAL13_350058600 ⚠
exosome-associated protein 4, putative
— Both
LPAL13_280036500 ⚠
heat-shock protein hsp70, putative
— OG6
LPAL13_220018400 ⚠
exosome complex exonuclease RRP45 homolog, pu
— Both
LPAL13_350038400 ⚠
exosome complex exonuclease RRP41, putative
— Both
LPAL13_230025100
Csl4p homologue, putative
— Both
LPAL13_250019900 ⚠
Conserved hypothetical ATP binding protein, p
— Both
LPAL13_260017100 ⚠
heat-shock protein hsp70, putative
— Both
LPAL13_140005000
exosome complex exonuclease, putative
— Both
LPAL13_320043200 ⚠
exosome-associated protein 2, putative
— Both
LPAL13_200012700 ⚠
elongation factor 1-beta
— Both
LPAL13_280018900 ⚠
heat-shock protein hsp70, putative
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.