LTRL590_140018900

'Cold-shock' DNA-binding domain containing protein, putative

Leishmania tropica L590 OG6: OG6_147036 OG7: OG7_0042945 71 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 71 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LTRL590_320041200 ⚠ chaperonin alpha subunit, putative	—	OG6 TCSYLVIO_005312 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_008271 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_010606	Both
LTRL590_270018500 ⚠ T-complex protein 1, beta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_008271 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_010606	OG7
LTRL590_080010500 ⚠ ribose-phosphate pyrophosphokinase, putative	—	OG7 TCSYLVIO_010606 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_010606	OG7
LTRL590_130005700 ⚠ mitochondrial DNA polymerase I protein B, put	—	OG7 TCSYLVIO_003485 ↔ TCSYLVIO_010606	OG7
LTRL590_130018000 ⚠ AAA domain/Dpy-30 motif containing protein, p	—	OG7 TCSYLVIO_000435 ↔ TCSYLVIO_010606	OG7
LTRL590_330009000 ⚠ ATP-binding cassette sub-family F member 1, p	—	OG7 TCSYLVIO_004518 ↔ TCSYLVIO_010606	OG7
LTRL590_190012800 ⚠ ABC transport system ATP-binding protein, put	—	OG7 TCSYLVIO_004518 ↔ TCSYLVIO_010606	OG7
LTRL590_030015300 ⚠ MORN repeat, putative	—	OG7 TCSYLVIO_001987 ↔ TCSYLVIO_010606	OG7
LTRL590_260005000 brix domain containing-like protein	—	OG6 TCSYLVIO_000956 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_000956 ↔ TCSYLVIO_010606	Both
LTRL590_360083200 ⚠ T-complex protein 1, theta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_008271 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_010606	OG7
LTRL590_110007600 ⚠ proteasome alpha 7 subunit, putative	—	OG6 TCSYLVIO_001707 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_009369 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005678 ↔ TCSYLVIO_010606	Both
LTRL590_120005300 ⚠ proteasome beta-1 subunit, putative	—	OG6 TCSYLVIO_006999 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_006999 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005774 ↔ TCSYLVIO_010606	Both
LTRL590_280015100 oxidoreductase-like protein	—	OG6 TCSYLVIO_002566 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_002566 ↔ TCSYLVIO_010606	Both
LTRL590_130021500 ⚠ mitochondrial DNA polymerase I protein D, put	—	OG6 TCSYLVIO_003485 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_003485 ↔ TCSYLVIO_010606	Both
LTRL590_280006100 proteasome beta 3 subunit, putative	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_010606	Both
LTRL590_060013700 lipin, putative	—	OG6 TCSYLVIO_001856 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_001856 ↔ TCSYLVIO_010606	Both
LTRL590_270026900 ⚠ Dpy-30 motif containing protein, putative	—	OG6 TCSYLVIO_000435 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_000435 ↔ TCSYLVIO_010606	Both
LTRL590_350055300 ⚠ proteasome alpha 1 subunit, putative	—	OG6 TCSYLVIO_005678 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_009369 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005678 ↔ TCSYLVIO_010606	Both
LTRL590_360022700 ⚠ proteasome alpha 1 subunit, putative	—	OG7 TCSYLVIO_001707 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_009369 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005678 ↔ TCSYLVIO_010606	OG7
LTRL590_200013800 ⚠ N-ethylmaleimide-sensitive factor, putative	—	OG7 Tb927.11.1680 ↔ Tb927.7.3810	OG7
LTRL590_350022600 ⚠ ubiquitin hydrolase, putative	—	OG7 TCSYLVIO_007047 ↔ TCSYLVIO_010606	OG7
LTRL590_140016200 ⚠ RNA editing 3' terminal uridylyl transferase	—	OG7 TCSYLVIO_005053 ↔ TCSYLVIO_010606	OG7
LTRL590_340046700 ⚠ ubiquitin hydrolase, putative	—	OG7 TCSYLVIO_007047 ↔ TCSYLVIO_010606	OG7
LTRL590_260008500 ⚠ RET2, RNA editing complex MP57	—	OG7 TCSYLVIO_005053 ↔ TCSYLVIO_010606	OG7
LTRL590_280013100 ⚠ RNA polymerase I	—	OG7 TCSYLVIO_005053 ↔ TCSYLVIO_010606	OG7
LTRL590_360023200 ⚠ proteasome beta 5 subunit, putative	—	OG7 TCSYLVIO_006999 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005774 ↔ TCSYLVIO_010606	OG7
LTRL590_270007000 ⚠ proteasome alpha 7 subunit, putative	—	OG7 TCSYLVIO_001707 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_009369 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005678 ↔ TCSYLVIO_010606	OG7
LTRL590_080014700 ⚠ phosphoribosylpyrophosphate synthetase	—	OG6 TCSYLVIO_010606 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_010606 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_010606	Both
LTRL590_140008800 ⚠ proteasome alpha 3 subunit, putative	—	OG7 TCSYLVIO_001707 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_009369 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005678 ↔ TCSYLVIO_010606	OG7
LTRL590_210027500 ⚠ proteasome subunit alpha type-5, putative	—	OG7 TCSYLVIO_001707 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_009369 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005678 ↔ TCSYLVIO_010606	OG7
LTRL590_120007200 ⚠ ubiquitin hydrolase, putative	—	OG7 TCSYLVIO_005373 ↔ TCSYLVIO_010606	OG7
LTRL590_350029500 ⚠ ubiquitin hydrolase, putative	—	OG7 TCSYLVIO_005373 ↔ TCSYLVIO_010606	OG7
LTRL590_270018700 ⚠ ubiquitin hydrolase, putative	—	OG7 TCSYLVIO_005373 ↔ TCSYLVIO_010606	OG7
LTRL590_130021800 ⚠ chaperonin TCP20, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_008271 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_010606	OG7
LTRL590_350045100 ⚠ T-complex protein 1, eta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_008271 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_010606	OG7
LTRL590_360039400 ⚠ ATP-dependent RNA helicase, putative	—	OG7 TCSYLVIO_004479 ↔ TCSYLVIO_010606	OG7
LTRL590_270029300 ⚠ Thioredoxin, putative	—	OG6 TCSYLVIO_000453 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_010606	Both
LTRL590_110007900 hypothetical protein, conserved	—	OG6 TCSYLVIO_001704 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_001704 ↔ TCSYLVIO_010606	Both
LTRL590_260013100 hypothetical protein, conserved	—	OG6 Tb927.7.1100 ↔ Tb927.7.3810 OG7 Tb927.7.1100 ↔ Tb927.7.3810	Both
LTRL590_180013600 hypothetical protein, conserved	—	OG6 TCSYLVIO_006208 ↔ TCSYLVIO_010606 OG6 TCSYLVIO_006209 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_006208 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_006209 ↔ TCSYLVIO_010606	Both
LTRL590_330026700 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG6 TCSYLVIO_004731 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_010606 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_010606	Both
LTRL590_360065700 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG6 TCSYLVIO_004731 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_010606 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_010606	Both
LTRL590_230011800 hypothetical protein, conserved	—	OG6 TCSYLVIO_000050 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_000050 ↔ TCSYLVIO_010606	Both
LTRL590_030012300 ⚠ DEAD/DEAH box helicase, putative	—	OG6 TCSYLVIO_004479 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_004479 ↔ TCSYLVIO_010606	Both
LTRL590_340035700 exosome subunit rrp6p homologue, putative	—	OG6 TCSYLVIO_003804 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_003804 ↔ TCSYLVIO_010606	Both
LTRL590_220020400 ⚠ exosome complex exonuclease RRP45 homolog, pu	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_010606	Both
LTRL590_320037700 ⚠ ATP binding protein-like protein	—	OG6 TCSYLVIO_000453 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_010606	Both
LTRL590_300039800 kinesin, putative	—	OG6 TCSYLVIO_003336 ↔ TCSYLVIO_010606	OG6
LTRL590_290021700 hypothetical protein, conserved	—	OG6 TCSYLVIO_004312 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_004312 ↔ TCSYLVIO_010606	Both
LTRL590_330030900 glycosyl hydrolase-like protein	—	OG6 TCSYLVIO_003461 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_003461 ↔ TCSYLVIO_010606	Both

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