LTRL590_340008700

eukaryotic translation initiation factor 5, putative

Leishmania tropica L590 OG6: OG6_101859 OG7: OG7_0007078 58 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Query Computational only Exp + computational Experimental only

Interactions 58 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LTRL590_070009100 ⚠ hypothetical protein	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
LTRL590_350055300 ⚠ proteasome alpha 1 subunit, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556	Both
LTRL590_330026700 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_004731 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_004731	Both
LTRL590_210026200 ⚠ proteasome alpha 2 subunit, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556	Both
LTRL590_350028100 ATP-dependent RNA helicase-like protein	—	OG6 TCSYLVIO_001373 ↔ TCSYLVIO_004556	OG6
LTRL590_300040000 eukaryotic translation initiation factor 3 su	—	OG6 TCSYLVIO_003333 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_003333 ↔ TCSYLVIO_004556	Both
LTRL590_310043600 ⚠ acetyl-CoA carboxylase, putative	—	OG6 TCSYLVIO_002772 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_004556	Both
LTRL590_310043700 ⚠ Carbamoyl-phosphate synthase L chain, N-termi	—	OG6 TCSYLVIO_002772 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_004556	Both
LTRL590_280006100 proteasome beta 3 subunit, putative	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_004556	Both
LTRL590_110007600 ⚠ proteasome alpha 7 subunit, putative	—	OG6 TCSYLVIO_001707 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556	Both
LTRL590_270018500 ⚠ T-complex protein 1, beta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	OG7
LTRL590_360083200 ⚠ T-complex protein 1, theta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	OG7
LTRL590_360039400 ⚠ ATP-dependent RNA helicase, putative	—	OG7 TCSYLVIO_004479 ↔ TCSYLVIO_004556	OG7
LTRL590_350045100 ⚠ T-complex protein 1, eta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	OG7
LTRL590_130021800 ⚠ chaperonin TCP20, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	OG7
LTRL590_360065700 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_004731 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_004731	Both
LTRL590_280028300 ⚠ mitochondrial DEAD box protein, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
LTRL590_210027500 ⚠ proteasome subunit alpha type-5, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556	OG7
LTRL590_080010500 ⚠ ribose-phosphate pyrophosphokinase, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_004731	OG7
LTRL590_360029000 ⚠ DEAD box RNA helicase, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
LTRL590_070009200 ⚠ ATP-dependent DEAD/H RNA helicase, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
LTRL590_190007500 ⚠ RNA binding protein, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_006059	OG7
LTRL590_360022700 ⚠ proteasome alpha 1 subunit, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556	OG7
LTRL590_270007000 ⚠ proteasome alpha 7 subunit, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556	OG7
LTRL590_360023200 ⚠ proteasome beta 5 subunit, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_006999	OG7
LTRL590_140008800 ⚠ proteasome alpha 3 subunit, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556	OG7
LTRL590_000021800 ⚠ DEAD/DEAH box helicase, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
LTRL590_320009100 ⚠ ATP-dependent RNA helicase, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
LTRL590_080005700 ⚠ ATP-dependent DEAD/H RNA helicase, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
LTRL590_360047800 ⚠ 60S ribosomal protein L10a, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_006190 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_006190	Both
LTRL590_340031800 RNA recognition motif. (a.k.a. RRM, RBD, or R	—	OG6 TCSYLVIO_003837 ↔ TCSYLVIO_004556	OG6
LTRL590_360060600 hypothetical protein, conserved	—	OG6 Tb927.10.2770 ↔ Tb927.11.11010 OG7 Tb927.10.2770 ↔ Tb927.11.11010	Both
LTRL590_320037700 ⚠ ATP binding protein-like protein	—	OG6 TCSYLVIO_000453 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_004556	Both
LTRL590_270029300 ⚠ Thioredoxin, putative	—	OG6 TCSYLVIO_000453 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_004556	Both
LTRL590_300011400 spliceosome-associated protein, putative	—	OG6 TCSYLVIO_003119 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_003119 ↔ TCSYLVIO_004556	Both
LTRL590_340035700 exosome subunit rrp6p homologue, putative	—	OG6 TCSYLVIO_003804 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_003804 ↔ TCSYLVIO_004556	Both
LTRL590_030012300 ⚠ DEAD/DEAH box helicase, putative	—	OG6 TCSYLVIO_004479 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004479 ↔ TCSYLVIO_004556	Both
LTRL590_110007900 hypothetical protein, conserved	—	OG6 TCSYLVIO_001704 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_001704 ↔ TCSYLVIO_004556	Both
LTRL590_220020400 ⚠ exosome complex exonuclease RRP45 homolog, pu	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004556	Both
LTRL590_320043200 ⚠ exosome-associated protein 2, putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004556	Both
LTRL590_320016500 ⚠ chaperonin containing t-complex protein, puta	—	OG6 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	Both
LTRL590_230021300 ⚠ T-complex protein 1, gamma subunit, putative	—	OG6 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	Both
LTRL590_030006100 acetyltransferase, putative	—	OG6 TCSYLVIO_004519 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004519 ↔ TCSYLVIO_004556	Both
LTRL590_350044900 ⚠ proteasome beta 2 subunit, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_006999	Both
LTRL590_290021700 hypothetical protein, conserved	—	OG6 TCSYLVIO_004312 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004312 ↔ TCSYLVIO_004556	Both
LTRL590_360019300 N-acetyltransferase subunit Nat1, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_010020 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_010020	Both
LTRL590_360044600 ⚠ 2-oxoglutarate dehydrogenase subunit, putativ	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_005469 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005469	Both
LTRL590_180011700 ⚠ 60S ribosomal protein L10a, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_006190 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_006190	Both
LTRL590_120005300 ⚠ proteasome beta-1 subunit, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_006999	Both
LTRL590_140018900 'Cold-shock' DNA-binding domain containing pr	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_010606	Both

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