LbrM.01.0400

hypothetical protein, conserved
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_157997 OG7: OG7_0051936 58 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 58 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.25.2450 ⚠
hypothetical protein, conserved
— OG7
LbrM.10.0360
hypothetical protein, conserved
— Both
LbrM.34.2110
hypothetical protein, conserved
— Both
LbrM.08.0730
Beta-lactamase superfamily domain containing
— Both
LbrM.08.0110
hypothetical protein, unknown function
— Both
LbrM.31.1940
hypothetical protein, conserved
— Both
LbrM.26.1670
hypothetical protein, conserved
— Both
LbrM.18.1230 ⚠
Ras-related protein Rab5A, putative
— OG6
LbrM.29.2670 ⚠
ras-related protein RAB5B, putative
— OG6
LbrM.20.5580 ⚠
pumilio protein, putative, RNA-binding regula
— OG7
LbrM.20.5610 ⚠
RNA-binding regulatory protein, putative, pum
— OG7
LbrM.12.0400 ⚠
pumillio protein 4, putative
— OG7
LbrM.25.1380 ⚠
hypothetical protein, conserved (fragment)
— OG7
LbrM.21.1990 ⚠
pumillio protein 3, putative
— OG7
LbrM.06.0050 ⚠
pumilio/PUF RNA binding protein 5, putative
— OG7
LbrM.29.1550
hypothetical protein, conserved
— Both
LbrM.35.0090 ⚠
PUF1, putative
— OG7
LbrM.35.4560 ⚠
hypothetical protein, conserved
— OG7
LbrM.34.1640 ⚠
ubiquitin hydrolase, putative, cysteine pepti
— OG7
LbrM.20.3690 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
LbrM.34.3160 ⚠
replication factor C, subunit 3, putative
— OG7
LbrM.20.2860 ⚠
Zn-finger in ubiquitin-hydrolases and other p
— OG7
LbrM.32.0850 ⚠
cyclin 9, putative
— OG7
LbrM.17.0530 ⚠
ATPase family associated with various cellula
— OG7
LbrM.30.2590 ⚠
replication factor C, subunit 2, putative
— OG7
LbrM.24.1000 ⚠
replication factor C, subunit 1, putative
— OG7
LbrM.35.7070 ⚠
replication factor C subunit 3, putative
— OG7
LbrM.27.0660 ⚠
replication factor C, subunit 4, putative
— OG7
LbrM.20.1650 ⚠
eukaryotic translation initiation factor 2-al
— OG7
LbrM.20.5000
hypothetical protein, conserved
— Both
LbrM.32.3500
Miro-like protein, putative
— Both
LbrM.18.1450 ⚠
pumilio protein, putative, pumilio protein 2,
— Both
LbrM.18.0300
hypothetical protein, conserved
— Both
LbrM.33.1360 ⚠
pumilio protein 6, putative
— Both
LbrM.35.4570 ⚠
predicted C2 domain protein
— Both
LbrM.30.3770
ribosomal P protein AGP2beta-1, putative
— Both
LbrM.34.1530
Concanavalin A-like lectin/glucanases superfa
— Both
LbrM.28.2690
hypothetical protein, conserved
— Both
LbrM.34.3270
Putative death-receptor fusion protein (DUF24
— Both
LbrM.19.0260 ⚠
protein kinase
— Both
LbrM.15.1240 ⚠
cysteine peptidase, Clan CA, family C19, puta
— Both
LbrM.19.0970
hypothetical protein, conserved
— Both
LbrM.35.5920 ⚠
Cyclin 12, L-type
— Both
LbrM.09.1580
hypothetical protein, conserved
— Both
LbrM.35.0710
Eukaryotic translation initiation factor 4E t
— Both
LbrM.35.2670
hypothetical protein, conserved
— Both
LbrM.25.1280 ⚠
DNA-directed RNA polymerase I subunit RPB10,
— Both
LbrM.20.1440 ⚠
kinesin, putative
— OG6
LbrM.21.1350
hypothetical protein, conserved
— Both
LbrM.30.2390
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.