LbrM.14.0850

hypothetical protein, conserved
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_478704 OG7: OG7_0043762 34 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 34 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.23.1810 ⚠
neutral sphingomyelinase activation associate
— OG7
LbrM.20.1950 ⚠
Sec7 domain containing protein, putative
— OG7
LbrM.20.2060 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LbrM.34.5330 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LbrM.30.1210 ⚠
WW domain containing protein, putative
— OG7
LbrM.16.1170 ⚠
WW domain containing protein, putative
— OG7
LbrM.30.1030 ⚠
ubiquitin-protein ligase, putative
— OG7
LbrM.35.1280 ⚠
endonuclease/exonuclease/phosphatase, putativ
— OG7
LbrM.20.5370 ⚠
dynein arm light chain, putative
— OG7
LbrM.11.0780
HIT zinc finger, putative
— Both
LbrM.33.1390 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
LbrM.15.1160 ⚠
inositol/phosphatidylinositol phosphatase, pu
— OG7
LbrM.12.0530 ⚠
WW domain containing protein, putative
— OG7
LbrM.34.4210 ⚠
hypothetical protein, conserved
— OG7
LbrM.23.0130 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LbrM.28.2590 ⚠
WW domain containing protein, putative
— OG7
LbrM.35.1910 ⚠
hypothetical protein, conserved
— OG7
LbrM.21.1250 ⚠
dynein arm light chain, putative
— Both
LbrM.07.0290 ⚠
ubiquitin-protein ligase-like, putative
— Both
LbrM.07.0540
Dynein heavy chain, N-terminal region 2, puta
— OG6
LbrM.23.0660
Galactose oxidase, central domain containing
— Both
LbrM.34.1560
hypothetical protein, conserved
— Both
LbrM.17.1250 ⚠
WW domain containing protein, putative
— Both
LbrM.33.1750
hypothetical protein, conserved
— Both
LbrM.21.1420
hypothetical protein, conserved
— Both
LbrM.33.3060 ⚠
Concanavalin A-like lectin/glucanases superfa
— Both
LbrM.07.0120 ⚠
Sec7 domain containing protein, putative
— Both
LbrM.33.2040
hypothetical protein, conserved
— Both
LbrM.30.1660
hypothetical protein, conserved
— Both
LbrM.24.0840 ⚠
inositol polyphosphate phosphatase, putative
— Both
LbrM.26.1140 ⚠
axonemal dynein light chain, putative
— Both
LbrM.31.0130
hypothetical protein, unknown function
— Both
LbrM.29.0840
hypothetical protein, conserved
— Both
LbrM.34.2590
hypothetical protein, conserved
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.