LbrM.07.0540

Dynein heavy chain, N-terminal region 2, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_139865 OG7: OG7_0000699 51 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 51 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.27.2690
hypothetical protein, conserved, WD-repeat pr
— OG6
LbrM.33.3060
Concanavalin A-like lectin/glucanases superfa
— OG6
LbrM.21.1250
dynein arm light chain, putative
— OG6
LbrM.19.1160 ⚠
kinesin, putative (fragment)
— OG6
LbrM.19.1150 ⚠
Flagellum attachment zone protein 7 (fragment
— OG6
LbrM.35.1120
intraflagellar transport protein 122, putativ
— OG6
LbrM.33.2040
hypothetical protein, conserved
— OG6
LbrM.30.1660
hypothetical protein, conserved
— OG6
LbrM.34.3990 ⚠
protein kinase A catalytic subunit isoform 1
— OG6
LbrM.32.0380
intraflagellar transport protein 140, putativ
— OG6
LbrM.24.0840
inositol polyphosphate phosphatase, putative
— OG6
LbrM.29.1260
hypothetical protein, conserved
— OG6
LbrM.26.1140
axonemal dynein light chain, putative
— OG6
LbrM.31.3550
Flagellum attachment zone protein 14
— OG6
LbrM.32.0320
hypothetical protein, conserved
— OG6
LbrM.30.2160
endosomal trafficking protein RME-8, putative
— OG6
LbrM.31.0130
hypothetical protein, unknown function
— OG6
LbrM.30.0740
pdz domain containing protein, putative
— OG6
LbrM.17.0410
hypothetical protein, conserved
— OG6
LbrM.29.0840
hypothetical protein, conserved
— OG6
LbrM.34.2590
hypothetical protein, conserved
— OG6
LbrM.04.0600
TPR repeat/Tetratricopeptide repeat, putative
— OG6
LbrM.03.0880
MORN repeat, putative
— OG6
LbrM.05.0190
Fip1 motif/Zinc finger C-x8-C-x5-C-x3-H type
— OG6
LbrM.04.0890
axonemal dynein light chain, putative
— OG6
LbrM.06.1140
hypothetical protein, conserved
— OG6
LbrM.21.1570
RecF/RecN/SMC N terminal domain/SMC proteins
— OG6
LbrM.05.0900
paraflagellar rod protein, putative
— OG6
LbrM.07.0290
ubiquitin-protein ligase-like, putative
— OG6
LbrM.35.6640
ubiquitin-protein ligase, putative
— OG6
LbrM.23.0660
Galactose oxidase, central domain containing
— OG6
LbrM.34.1560
hypothetical protein, conserved
— OG6
LbrM.19.1000 ⚠
Flagellum attachment zone protein 7
— OG6
LbrM.12.0610
TPR repeat, putative
— OG6
LbrM.21.1960
hypothetical protein, conserved
— OG6
LbrM.19.1290
WD domain, G-beta repeat, putative
— OG6
LbrM.23.0020
hypothetical protein, conserved
— OG6
LbrM.09.1270
AAA family ATPase, putative
— OG6
LbrM.30.0800
CDC16, putative
— OG6
LbrM.07.0120
Sec7 domain containing protein, putative
— OG6
LbrM.15.0760
hypothetical protein, unknown function
— OG6
LbrM.17.1250
WW domain containing protein, putative
— OG6
LbrM.22.1540
ccr4-not transcription complex subunit
— OG6
LbrM.18.1180 ⚠
protein kinase A catalytic subunit 3
— OG6
LbrM.11.0780
HIT zinc finger, putative
— OG6
LbrM.30.0060
MATH domain containing protein, putative
— OG6
LbrM.33.1750
hypothetical protein, conserved
— OG6
LbrM.20.5280
phosphatidylinositol 3-kinase, putative
— OG6
LbrM.21.1420
hypothetical protein, conserved
— OG6
LbrM.14.0850
hypothetical protein, conserved
— OG6
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.