LbrM.25.0310

hypothetical protein, conserved
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_478624 OG7: OG7_0052123 21 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 21 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.32.1280 ⚠
hypothetical protein, conserved
— Both
LbrM.34.4310 ⚠
pre-RNA processing PIH1/Nop17, putative
— OG7
LbrM.20.2060 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LbrM.07.0120 ⚠
Sec7 domain containing protein, putative
— OG7
LbrM.16.1380
hypothetical protein, conserved
— OG7
LbrM.15.0710
hypothetical protein, conserved
— Both
LbrM.35.7360
eukaryotic translation initiation factor 3 su
— Both
LbrM.34.0610
hypothetical protein, conserved
— Both
LbrM.32.1230 ⚠
hypothetical protein, conserved (fragment)
— Both
LbrM.31.1200
hypothetical protein, conserved
— Both
LbrM.30.3050
kinesin, putative
— OG6
LbrM.18.1330 ⚠
pre-RNA processing PIH1/Nop17, putative
— Both
LbrM.32.3090
CS domain/TPR repeat/Tetratricopeptide repeat
— Both
LbrM.30.3030
eukaryotic translation initiation factor 3 su
— Both
LbrM.28.2830
Coatomer subunit gamma
— Both
LbrM.29.1170
hypothetical protein, conserved
— Both
LbrM.20.1950 ⚠
Sec7 domain containing protein, putative
— Both
LbrM.25.2400
Eukaryotic translation initiation factor 3 su
— Both
LbrM.26.2300
SPRY domain/HECT-domain (ubiquitin-transferas
— Both
LbrM.22.1150
hypothetical protein, conserved
— Both
LbrM.04.0580
hypothetical protein, conserved
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.