LbrM.18.1330

pre-RNA processing PIH1/Nop17, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_105060 OG7: OG7_0006226 67 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 67 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.32.3090 ⚠
CS domain/TPR repeat/Tetratricopeptide repeat
— Both
LbrM.35.6620 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
LbrM.04.0550 ⚠
Nucleotidyltransferase domain containing prot
— OG7
LbrM.08.0600 ⚠
eukaryotic translation initiation factor 2 be
— OG7
LbrM.28.2950 ⚠
receptor for activated C kinase 1
— OG7
LbrM.32.1620 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LbrM.20.3990 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
LbrM.20.5280 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LbrM.02.0130 ⚠
phosphatidylinositol kinase related protein,
— OG7
LbrM.26.0510 ⚠
DNA polymerase sigma-like protein
— OG7
LbrM.35.3160 ⚠
phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LbrM.23.0850 ⚠
mitochondrial RNA binding protein, putative
— Both
LbrM.14.0440 ⚠
mRNA capping enzyme, beta chain, putative
— Both
LbrM.14.0300 ⚠
hypothetical protein, conserved
— Both
LbrM.21.1340
U4/U6 small nuclear ribonuclear protein, puta
— OG6
LbrM.18.1520 ⚠
NADH-ubiquinone oxidoreductase complex I subu
— Both
LbrM.35.5490 ⚠
glycosyl hydrolase, putative
— Both
LbrM.15.0710 ⚠
hypothetical protein, conserved
— Both
LbrM.31.2980 ⚠
2-oxoglutarate dehydrogenase, e3 component, l
— Both
LbrM.07.0770 ⚠
topoisomerase-related function protein-like p
— OG7
LbrM.30.1510 ⚠
WD domain, G-beta repeat, putative
— OG7
LbrM.31.0230 ⚠
dihydrolipoamide dehydrogenase
— OG7
LbrM.33.1800 ⚠
elongation factor 1-gamma, putative
— OG7
LbrM.12.0380 ⚠
Glutathione S-transferase, N-terminal domain
— OG7
LbrM.05.1110 ⚠
DNA-directed RNA polymerase I largest subunit
— OG7
LbrM.31.2950 ⚠
RNA polymerase ii largest subunit
— OG7
LbrM.16.1400 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
LbrM.20.0330 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
LbrM.32.4110 ⚠
myosin XXI, putative
— OG7
LbrM.07.0120 ⚠
Sec7 domain containing protein, putative
— OG7
LbrM.14.1130 ⚠
hypothetical protein, conserved
— OG7
LbrM.24.0280 ⚠
Dynein intermediate chain 1, axonemal
— OG7
LbrM.29.0110 ⚠
hypothetical protein, conserved
— OG7
LbrM.20.2060 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LbrM.25.0310 ⚠
hypothetical protein, conserved
— Both
LbrM.21.2160 ⚠
hypothetical protein, conserved
— Both
LbrM.20.0970 ⚠
myosin IB heavy chain, putative
— Both
LbrM.26.2080 ⚠
hypothetical protein, unknown function
— Both
LbrM.24.1070 ⚠
AKAP7 2'5' RNA ligase-like domain containing
— Both
LbrM.30.3030 ⚠
eukaryotic translation initiation factor 3 su
— Both
LbrM.20.5560 ⚠
coatomer beta subunit, putative
— Both
LbrM.28.2830 ⚠
Coatomer subunit gamma
— Both
LbrM.20.3930 ⚠
coatomer alpha subunit, putative
— Both
LbrM.32.1280 ⚠
hypothetical protein, conserved
— Both
LbrM.29.1170 ⚠
hypothetical protein, conserved
— Both
LbrM.33.1850 ⚠
hypothetical protein, conserved
— Both
LbrM.20.1950 ⚠
Sec7 domain containing protein, putative
— Both
LbrM.25.2400 ⚠
Eukaryotic translation initiation factor 3 su
— Both
LbrM.26.2300 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— Both
LbrM.09.1020 ⚠
elongation factor-1 gamma
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.