LbrM.28.0130

DNA-direcetd RNA polymerase II, subunit 9, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_102455 OG7: OG7_0002891 53 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 53 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.10.1070 ⚠
histone H3
— OG7
LbrM.21.1150 ⚠
histone H2A, putative
— OG7
LbrM.21.1140 ⚠
histone H2A
— OG7
LbrM.16.1400 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
LbrM.32.1270 ⚠
histone H2A, putative
— OG7
LbrM.07.0400 ⚠
RAVE protein 1 C terminal, putative
— OG7
LbrM.15.0710 ⚠
hypothetical protein, conserved
— OG7
LbrM.22.1500 ⚠
hypothetical protein, conserved
— OG7
LbrM.04.0550 ⚠
Nucleotidyltransferase domain containing prot
— OG7
LbrM.26.0510 ⚠
DNA polymerase sigma-like protein
— OG7
LbrM.07.0770 ⚠
topoisomerase-related function protein-like p
— OG7
LbrM.03.0340 ⚠
protein kinase, putative
— OG7
LbrM.35.5490 ⚠
glycosyl hydrolase, putative
— OG7
LbrM.18.0880 ⚠
DNA-directed RNA polymerase I subunit RPB5z,
— OG7
LbrM.05.1110 ⚠
DNA-directed RNA polymerase I largest subunit
— OG7
LbrM.10.1080 ⚠
histone H3
— OG7
LbrM.10.1090 ⚠
histone H3
— OG7
LbrM.10.0970 ⚠
histone H3
— OG7
LbrM.19.0950 ⚠
histone H3 variant V
— OG7
LbrM.34.0330 ⚠
hypothetical protein, conserved
— OG7
LbrM.34.5350 ⚠
hypothetical protein, conserved (fragment)
— OG7
LbrM.09.1120 ⚠
DNA-directed RNA polymerase III subunit, puta
— OG7
LbrM.04.0170 ⚠
exosome complex exonuclease RRP40, putative
— OG7
LbrM.04.0710 ⚠
hypothetical protein
— OG7
LbrM.26.0610 ⚠
hypothetical protein, conserved
— OG7
LbrM.21.0910 ⚠
Temperature dependent protein affecting M2 ds
— OG7
LbrM.30.3470 ⚠
protein mkt1, putative
— OG7
LbrM.25.0140 ⚠
DNA-directed RNA polymerase I subunit, putati
— Both
LbrM.20.4090 ⚠
DNA-directed RNA polymerase III, putative
— Both
LbrM.29.0150 ⚠
DNA-directed RNA polymerase II subunit 3, put
— Both
LbrM.31.0270 ⚠
DNA-directed RNA polymerase II subunit 2, put
— Both
LbrM.20.0860 ⚠
DNA-directed RNA polymerase III subunit, puta
— Both
LbrM.28.2250 ⚠
DNA-directed RNA polymerase-like protein
— Both
LbrM.25.1280 ⚠
DNA-directed RNA polymerase I subunit RPB10,
— Both
LbrM.20.0330 ⚠
DNA-directed RNA polymerase III subunit C1, p
— Both
LbrM.29.0340 ⚠
RNA polymerase Rpb4, putative
— Both
LbrM.13.0920 ⚠
RNA-binding protein RBP10, putative, DNA-dire
— Both
LbrM.31.2950 ⚠
RNA polymerase ii largest subunit
— Both
LbrM.28.0850 ⚠
RNA polymerase B subunit RPB8, putative
— Both
LbrM.18.0870 ⚠
DNA-directed RNA polymerase II/III subunit, p
— Both
LbrM.32.1440 ⚠
RNA polymerase-like protein, putative
— Both
LbrM.20.4730 ⚠
hypothetical protein, conserved
— Both
LbrM.27.1690 ⚠
DNA-directed RNA polymerase II-like protein
— Both
LbrM.15.0510 ⚠
Galactose oxidase, central domain/Kelch motif
— OG7
LbrM.20.5570 ⚠
exosome-associated protein 1, putative
— OG7
LbrM.31.1440 ⚠
Protein of unknown function (DUF3638)/Protein
— OG7
LbrM.25.2130 ⚠
RNA polymerase I second largest subunit, puta
— OG7
LbrM.21.1160 ⚠
histone H2A, putative
— OG7
LbrM.17.0260 ⚠
histone H2A variant Z
— OG7
LbrM.29.1810 ⚠
histone H2A, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.