LbrM.32.0780 – TrypsnetDB2

LbrM.32.0780

ubiquitin-conjugating enzyme E2, putative

Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_102420 OG7: OG7_0006962 19 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Interactions 19 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LbrM.34.5280 Dynein heavy chain and region D6 of dynein mo	—	OG6 TCSYLVIO_004229 ↔ TCSYLVIO_005636 OG7 TCSYLVIO_004229 ↔ TCSYLVIO_005636	Both
LbrM.17.0240 hypothetical protein, conserved	—	OG7 TCSYLVIO_004229 ↔ TCSYLVIO_009109	OG7
LbrM.04.1100 hypothetical protein, conserved	—	OG7 TCSYLVIO_004229 ↔ TCSYLVIO_007195	OG7
LbrM.35.1910 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_000384 ↔ TCSYLVIO_004229	OG7
LbrM.23.0130 ⚠ Concanavalin A-like lectin/glucanases superfa	—	OG7 TCSYLVIO_000384 ↔ TCSYLVIO_004229	OG7
LbrM.23.1810 ⚠ neutral sphingomyelinase activation associate	—	OG7 TCSYLVIO_000384 ↔ TCSYLVIO_004229	OG7
LbrM.30.2790 ⚠ chaperonin HSP60/CNP60, putative	—	OG7 TCSYLVIO_004120 ↔ TCSYLVIO_004229	OG7
LbrM.11.0810 inositol-1,4,5-trisphosphate (IP3) 5-phosphat	—	OG6 TCSYLVIO_001632 ↔ TCSYLVIO_004229 OG7 TCSYLVIO_001632 ↔ TCSYLVIO_004229	Both
LbrM.30.1800 microtubule associated protein xmap215	—	OG6 TCSYLVIO_003218 ↔ TCSYLVIO_004229 OG7 TCSYLVIO_003218 ↔ TCSYLVIO_004229	Both
LbrM.27.0700 Domain of unknown function (DUF4470)/Domain o	—	OG6 TCSYLVIO_004229 ↔ TCSYLVIO_005450 OG7 TCSYLVIO_004229 ↔ TCSYLVIO_005450	Both
LbrM.33.3060 ⚠ Concanavalin A-like lectin/glucanases superfa	—	OG6 TCSYLVIO_000384 ↔ TCSYLVIO_004229 OG7 TCSYLVIO_000384 ↔ TCSYLVIO_004229	Both
LbrM.33.2070 hypothetical protein, conserved	—	OG6 TCSYLVIO_004229 ↔ TCSYLVIO_005629 OG7 TCSYLVIO_004229 ↔ TCSYLVIO_005629	Both
LbrM.13.1340 hypothetical protein, conserved	—	OG6 TCSYLVIO_004229 ↔ TCSYLVIO_004375 OG7 TCSYLVIO_004229 ↔ TCSYLVIO_004375	Both
LbrM.35.3440 hypothetical protein, conserved	—	OG6 TCSYLVIO_004229 ↔ TCSYLVIO_009213 OG7 TCSYLVIO_004229 ↔ TCSYLVIO_009213	Both
LbrM.35.2380 hypothetical protein, conserved	—	OG6 TCSYLVIO_004229 ↔ TCSYLVIO_004995 OG7 TCSYLVIO_004229 ↔ TCSYLVIO_004995	Both
LbrM.35.2240 ⚠ chaperonin HSP60, mitochondrial precursor	—	OG6 TCSYLVIO_004120 ↔ TCSYLVIO_004229 OG7 TCSYLVIO_004120 ↔ TCSYLVIO_004229	Both
LbrM.32.2030 ⚠ Chaperonin HSP60, mitochondrial	—	OG6 TCSYLVIO_004120 ↔ TCSYLVIO_004229 OG7 TCSYLVIO_004120 ↔ TCSYLVIO_004229	Both
LbrM.35.2250 ⚠ chaperonin HSP60, mitochondrial precursor	—	OG6 TCSYLVIO_004120 ↔ TCSYLVIO_004229 OG7 TCSYLVIO_004120 ↔ TCSYLVIO_004229	Both
LbrM.13.0570 hypothetical protein, conserved	—	OG6 TCSYLVIO_002806 ↔ TCSYLVIO_004229 OG7 TCSYLVIO_002806 ↔ TCSYLVIO_004229	Both

Orthogroup expansion — connections between the query proteins

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