LmxM.18.1240

pre-RNA processing PIH1/Nop17, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_105060 OG7: OG7_0006226 69 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 69 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.31.2850 ⚠
CS domain/TPR repeat/Tetratricopeptide repeat
— Both
LmxM.36.2940 ⚠
phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LmxM.36.3991 ⚠
hypothetical protein
— OG7
LmxM.07.0700 ⚠
topoisomerase-related function protein-like p
— OG7
LmxM.28.2750partial ⚠
hypothetical protein
— OG7
LmxM.26.0490 ⚠
DNA polymerase sigma-like protein
— OG7
LmxM.08_29.1830 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
LmxM.33.4530 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
LmxM.20.1120 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LmxM.36.0580 ⚠
hypothetical protein, unknown function
— OG7
LmxM.02.0120 ⚠
phosphatidylinositol 3-kinase-like protein
— OG7
LmxM.36.6320 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
LmxM.31.1460 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LmxM.36.5240 ⚠
glycosyl hydrolase, putative
— Both
LmxM.18.1480 ⚠
NADH-ubiquinone oxidoreductase complex I subu
— Both
LmxM.21.1120
U4/U6 small nuclear ribonuclear protein, puta
— OG6
LmxM.14.0430 ⚠
mRNA capping enzyme, beta chain, putative
— Both
LmxM.14.0300 ⚠
hypothetical protein, conserved
— Both
LmxM.30.2610 ⚠
RNA polymerase ii largest subunit
— OG7
LmxM.14.1130 ⚠
hypothetical protein, conserved
— OG7
LmxM.33.2520 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LmxM.24.0280 ⚠
Dynein intermediate chain 1, axonemal
— OG7
LmxM.07.0120 ⚠
Sec7 domain containing protein, putative
— OG7
LmxM.08_29.0100 ⚠
hypothetical protein, conserved
— OG7
LmxM.31.3870 ⚠
myosin XXI, putative
— OG7
LmxM.16.1350 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
LmxM.33.0360 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
LmxM.28.2740 ⚠
activated protein kinase c receptor (LACK)
— OG7
LmxM.32.1540 ⚠
elongation factor 1-gamma, putative
— OG7
LmxM.12.0360 ⚠
Glutathione S-transferase, N-terminal domain
— OG7
LmxM.28.2740a ⚠
hypothetical protein
— OG7
LmxM.29.1400 ⚠
WD domain, G-beta repeat, putative
— OG7
LmxM.08.0550 ⚠
translation initiation factor-like protein
— OG7
LmxM.04.0500 ⚠
Nucleotidyltransferase domain containing prot
— OG7
LmxM.14.1430 ⚠
Cilia and flagella associated protein 44, put
— Both
LmxM.29.3040 ⚠
eukaryotic translation initiation factor 3 su
— Both
LmxM.26.2160 ⚠
hypothetical protein, unknown function
— Both
LmxM.22.1270 ⚠
hypothetical protein, conserved
— Both
LmxM.20.1350 ⚠
coatomer beta subunit, putative
— Both
LmxM.25.1610 ⚠
Eukaryotic translation initiation factor 3 su
— Both
LmxM.33.0870 ⚠
hypothetical protein, conserved
— Both
LmxM.36.6980 ⚠
eukaryotic translation initiation factor 3 su
— Both
LmxM.32.1580 ⚠
hypothetical protein, conserved
— Both
LmxM.28.2620 ⚠
Coatomer subunit gamma
— Both
LmxM.25.0310 ⚠
hypothetical protein, conserved
— Both
LmxM.33.2450 ⚠
Sec7 domain containing protein, putative
— Both
LmxM.33.4310 ⚠
coatomer alpha subunit, putative
— Both
LmxM.08_29.1110 ⚠
hypothetical protein, conserved
— Both
LmxM.31.1130 ⚠
hypothetical protein, conserved
— Both
LmxM.30.1000 ⚠
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.