TcIL3000.11.15250

chaperonin HSP60, mitochondrial precursor
Trypanosoma congolense IL3000 OG6: OG6_100393 OG7: OG7_0003335 47 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 47 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_0_40210 ⚠
heat shock 70 kDa protein, putative (fragment
— OG6
TcIL3000_0_56480 ⚠
hypothetical protein (fragment)
— Both
TcIL3000_0_32710 ⚠
mitochondrial RNA binding protein 1
— Both
TcIL3000_8_1640 ⚠
hypothetical protein, conserved
— Both
TcIL3000_0_54460 ⚠
heat shock 70 kDa protein, putative
— OG6
TcIL3000.11.11990 ⚠
luminal binding protein 1 (BiP), putative
— OG6
TcIL3000_7_6050 ⚠
ATP synthase F1, alpha subunit, putative
— Both
TcIL3000_9_4610 ⚠
hypothetical protein, conserved
— Both
TcIL3000.11.11940 ⚠
heat shock 70 kDa protein, putative
— OG6
TcIL3000_0_08300 ⚠
heat shock 70 kDa protein, putative
— Both
TcIL3000_0_14230 ⚠
hypothetical protein, conserved
— Both
TcIL3000.11.11980 ⚠
heat shock protein 70, putative
— OG6
TcIL3000_0_15200 ⚠
hypothetical protein, conserved
— Both
TcIL3000_0_40200 ⚠
heat shock 70 kDa protein, putative
— OG6
TcIL3000.11.5900 ⚠
Archaic Translocase of outer membrane 14 kDa
— Both
TcIL3000_10_2180 ⚠
malate dehydrogenase-related
— OG7
TcIL3000_10_13190 ⚠
glycosomal malate dehydrogenase, putative
— OG7
TcIL3000_10_5200 ⚠
neurobeachin/beige protein, putative
— OG7
TcIL3000_0_42730 ⚠
Beige/BEACH domain containing protein, putati
— OG7
TcIL3000_10_5210 ⚠
neurobeachin/beige protein, putative (fragmen
— OG7
TcIL3000_0_01620 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
TcIL3000_0_00730 ⚠
neurobeachin/beige protein, putative (fragmen
— OG7
TcIL3000_0_48840 ⚠
neurobeachin/beige protein, putative
— OG7
TcIL3000_0_36120 ⚠
neurobeachin/beige protein, putative
— OG7
TcIL3000_0_50920 ⚠
cytoskeleton-associated protein, putative
— Both
TcIL3000_0_37380 ⚠
hypothetical protein (fragment)
— Both
TcIL3000.11.4180 ⚠
hypothetical protein, conserved
— Both
TcIL3000.11.10010 ⚠
hypothetical protein, conserved
— Both
TcIL3000.11.2950 ⚠
hypothetical protein, conserved
— Both
TcIL3000_0_09430 ⚠
hypothetical protein, conserved
— Both
TcIL3000_7_5240 ⚠
hypothetical protein, conserved
— Both
TcIL3000_9_3140 ⚠
Ankyrin repeats (3 copies), putative
— Both
TcIL3000.11.1160 ⚠
Domain of unknown function (DUF4470)/Domain o
— Both
TcIL3000.11.14310 ⚠
ubiquitin-conjugating enzyme E2, putative
— Both
TcIL3000_10_2350 ⚠
START domain containing protein, putative
— Both
TcIL3000_10_2190 ⚠
mitochondrial malate dehydrogenase
— Both
TcIL3000_0_07290 ⚠
paraflagellar rod component, putative
— Both
TcIL3000_6_2620 ⚠
microtubule associated protein xmap215
— Both
TcIL3000_0_42340 ⚠
cytoskeleton-associated protein, putative (fr
— Both
TcIL3000.11.6810 ⚠
inositol-1,4,5-trisphosphate (IP3) 5-phosphat
— Both
TcIL3000_0_27070 ⚠
heat shock 70 kDa protein, putative
— Both
TcIL3000.11.13660 ⚠
mitochondrial import inner membrane transloca
— Both
TcIL3000_0_40190 ⚠
heat shock protein 70 (hsp70), putative
— OG6
TcIL3000_0_02950 ⚠
heat shock 70 kDa protein, putative
— OG6
TcIL3000_6_1250 ⚠
zinc finger protein, putative
— Both
TcIL3000_0_21650 ⚠
Hsp70 protein, putative (fragment)
— OG6
TcIL3000_0_55930 ⚠
heat shock 70 kDa protein, putative
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.