TcIL3000_0_33600

Rab3 GTPase-activating protein catalytic subunit, putative (fragment)
Trypanosoma congolense IL3000 OG6: OG6_163794 OG7: OG7_0066788 125 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 125 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_0_57110 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
TcIL3000_7_3400 ⚠
WD domain, G-beta repeat/Dip2/Utp12 Family, p
— Both
TcIL3000_8_5970 ⚠
hypothetical protein, conserved
— Both
TcIL3000_5_1110 ⚠
exosome component CSL4, putative
— Both
TcIL3000_5_3890 ⚠
ubiquitin-activating enzyme E1, putative
— Both
TcIL3000_0_18970 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
TcIL3000_9_2550 ⚠
hypothetical protein
— OG6
TcIL3000_0_54930 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
TcIL3000_9_2560 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
TcIL3000_0_41520 ⚠
tubulin tyrosine ligase, putative (fragment)
— Both
TcIL3000_5_4350 ⚠
tubulin tyrosine ligase, putative
— Both
TcIL3000_0_42730 ⚠
Beige/BEACH domain containing protein, putati
— Both
TcIL3000_0_01620 ⚠
Concanavalin A-like lectin/glucanases superfa
— Both
TcIL3000_0_51360 ⚠
RNA polymerase beta subunit/RNA polymerase Rp
— OG7
TcIL3000_0_32940 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
TcIL3000_0_29100 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
TcIL3000_1_120 ⚠
DNA-directed RNA polymerase III, putative
— OG7
TcIL3000_4_3350 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
TcIL3000_1_900 ⚠
tubulin-tyrosine ligase, putative
— OG7
TcIL3000_10_11810 ⚠
tubulin tyrosine ligase protein, putative
— OG7
TcIL3000_0_10970 ⚠
Tubulin-tyrosine ligase family, putative (fra
— OG7
TcIL3000.11.7370 ⚠
tubulin-tyrsoine ligase-like protein, putativ
— OG7
TcIL3000_3_3320 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
TcIL3000_9_3430 ⚠
tubulin tyrosine ligase protein, putative
— OG7
TcIL3000_0_21510 ⚠
tubulin-tyrsoine ligase-like protein, putativ
— OG7
TcIL3000_2_1360 ⚠
tubulin-tyrosine ligase, putative
— OG7
TcIL3000_0_03330 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_02690 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
TcIL3000_0_22010 ⚠
cullin 1, putative
— OG7
TcIL3000_8_5720 ⚠
cullin, putative
— OG7
TcIL3000_8_5040 ⚠
cullin, putative
— OG7
TcIL3000_10_6450 ⚠
cullin, putative
— OG7
TcIL3000.11.14950 ⚠
Phosphatidylinositol 3- and 4-kinase/FATC dom
— OG7
TcIL3000_0_41600 ⚠
SpoU rRNA Methylase family, putative
— OG7
TcIL3000.11.14960 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
TcIL3000_10_7280 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
TcIL3000_1_1110 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
TcIL3000_8_7580 ⚠
acetoin dehydrogenase e3 component, putative,
— OG7
TcIL3000_4_4310 ⚠
dihydrolipoamide dehydrogenase, point mutatio
— OG7
TcIL3000_7_4310 ⚠
SpoU rRNA Methylase family, putative
— OG7
TcIL3000_4_110 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
TcIL3000_10_4210 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
TcIL3000_7_2940 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
TcIL3000_8_6400 ⚠
SpoU rRNA Methylase family, putative
— OG7
TcIL3000_2_150 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcIL3000_2_140 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcIL3000_0_50650 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
TcIL3000_10_6910 ⚠
beta adaptin, putative
— OG7
TcIL3000_10_2390 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
TcIL3000_10_5200 ⚠
neurobeachin/beige protein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.