TcIL3000_4_2170 – TrypsnetDB2

TcIL3000_4_2170

twinfilin

Trypanosoma congolense IL3000 OG6: OG6_102985 OG7: OG7_0051171 19 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Interactions 19 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TcIL3000_10_7200 ⚠ ribonuclease, putative	—	OG6 TCSYLVIO_003869 ↔ TCSYLVIO_004635 OG7 TCSYLVIO_003869 ↔ TCSYLVIO_004635	Both
TcIL3000_9_5730 ⚠ ribonuclease, putative	—	OG7 TCSYLVIO_003869 ↔ TCSYLVIO_004635	OG7
TcIL3000_0_10480 ⚠ methyltransferase domain containing protein,	—	OG7 TCSYLVIO_003869 ↔ TCSYLVIO_004270	OG7
TcIL3000_5_820 ⚠ mitochondrial processing peptidase, beta subu	—	OG7 TCSYLVIO_003423 ↔ TCSYLVIO_003869	OG7
TcIL3000.11.4260 U-box domain containing protein, putative	—	OG6 TCSYLVIO_002066 ↔ TCSYLVIO_003869 OG7 TCSYLVIO_002066 ↔ TCSYLVIO_003869	Both
TcIL3000.11.9780 phosphonopyruvate decarboxylase-like protein,	—	OG6 TCSYLVIO_002596 ↔ TCSYLVIO_003869 OG7 TCSYLVIO_002596 ↔ TCSYLVIO_003869	Both
TcIL3000_5_1030 ⚠ choline/ethanolamine kinase	—	OG6 TCSYLVIO_003869 ↔ TCSYLVIO_007612 OG7 TCSYLVIO_003869 ↔ TCSYLVIO_007612	Both
TcIL3000_8_1790 pitrilysin-like metalloprotease, putative, me	—	OG6 TCSYLVIO_003869 ↔ TCSYLVIO_009816 OG7 TCSYLVIO_003869 ↔ TCSYLVIO_009816	Both
TcIL3000_10_3810 predicted SET domain protein, hypothetical pr	—	OG6 TCSYLVIO_003869 ↔ TCSYLVIO_009938 OG7 TCSYLVIO_003869 ↔ TCSYLVIO_009938	Both
TcIL3000_0_38310 UDP-galactose 4-epimerase	—	OG6 TCSYLVIO_003869 ↔ TCSYLVIO_005587 OG7 TCSYLVIO_003869 ↔ TCSYLVIO_005587	Both
TcIL3000_9_490 kynureninase, putative	—	OG6 TCSYLVIO_003624 ↔ TCSYLVIO_003869 OG7 TCSYLVIO_003624 ↔ TCSYLVIO_003869	Both
TcIL3000_5_990 ⚠ choline/ethanolamine kinase, putative	—	OG6 TCSYLVIO_003869 ↔ TCSYLVIO_007612 OG7 TCSYLVIO_003869 ↔ TCSYLVIO_007612	Both
TcIL3000_0_41370 ⚠ Poly(A)-specific ribonuclease PARN-1	—	OG6 TCSYLVIO_003869 ↔ TCSYLVIO_004635 OG7 TCSYLVIO_003869 ↔ TCSYLVIO_004635	Both
TcIL3000_3_2990 ⚠ 5-histidylcysteine sulfoxide synthase, putati	—	OG6 TCSYLVIO_003869 ↔ TCSYLVIO_004270 OG7 TCSYLVIO_003869 ↔ TCSYLVIO_004270	Both
TcIL3000_0_36880 NAD+ synthase, putative	—	OG6 TCSYLVIO_003869 ↔ TCSYLVIO_004136 OG7 TCSYLVIO_003869 ↔ TCSYLVIO_004136	Both
TcIL3000_5_2790 otubain cysteine peptidase, Clan CA, family C	—	OG6 TCSYLVIO_003869 ↔ TCSYLVIO_008886 OG7 TCSYLVIO_003869 ↔ TCSYLVIO_008886	Both
TcIL3000_10_4850 The ARF-like 2 binding protein BART, putative	—	OG6 TCSYLVIO_003869 ↔ TCSYLVIO_004918 OG7 TCSYLVIO_003869 ↔ TCSYLVIO_004918	Both
TcIL3000_6_2960 NUDIX hydrolase domain-like domain-containing	—	OG6 TCSYLVIO_003248 ↔ TCSYLVIO_003869 OG7 TCSYLVIO_003248 ↔ TCSYLVIO_003869	Both
TcIL3000_9_1510 ⚠ mitochondrial-processing peptidase subunit be	—	OG6 TCSYLVIO_003423 ↔ TCSYLVIO_003869 OG7 TCSYLVIO_003423 ↔ TCSYLVIO_003869	Both

Orthogroup expansion — connections between the query proteins

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