TcIL3000_5_3160

histone deacetylase 4
Trypanosoma congolense IL3000 OG6: OG6_100220 OG7: OG7_0001154 81 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 81 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000.11.14890 ⚠
ATP-dependent DNA DEAD/DEAH box helicase, put
— OG7
TcIL3000_3_3450 ⚠
DNA-directed RNA polymerase II subunit 3, put
— OG7
TcIL3000.11.16020 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcIL3000_10_11620 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
TcIL3000_7_1320 ⚠
zinc finger protein, putative
— OG7
TcIL3000_0_38710 ⚠
ubiquitin-protein ligase, putative
— OG7
TcIL3000_10_5850 ⚠
Gamma-tubulin complex component 3-like protei
— OG7
TcIL3000_9_5850 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_47810 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcIL3000.11.15970 ⚠
zinc finger protein, putative
— OG7
TcIL3000.11.9950 ⚠
tubulin binding cofactor c, putative
— OG7
TcIL3000_10_7240 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
TcIL3000_10_7230 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
TcIL3000_0_24140 ⚠
DNA-directed RNA polymerase II subunit 3, put
— OG7
TcIL3000_9_4140 ⚠
predicted zinc finger protein
— OG7
TcIL3000_9_4850 ⚠
zinc finger protein, putative (fragment)
— OG7
TcIL3000_10_8190 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcIL3000_5_3230 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcIL3000.11.2790 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
TcIL3000_0_60440 ⚠
ribose-phosphate pyrophosphokinase, putative
— Both
TcIL3000_5_3590 ⚠
ribose-phosphate pyrophosphokinase, putative
— Both
TcIL3000_8_3410 ⚠
DNA polymerase theta (helicase domain only),
— OG7
TcIL3000_10_9180 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
TcIL3000_10_13320 ⚠
ABC transporter, putative
— OG7
TcIL3000_10_600 ⚠
structural maintenance of chromosome 4, putat
— OG7
TcIL3000_9_4840 ⚠
structural maintenance of chromosome 1, putat
— OG7
TcIL3000_10_8800 ⚠
structural maintenance of chromosome 2, putat
— OG7
TcIL3000_0_11960 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
TcIL3000_0_55120 ⚠
hypothetical protein
— OG7
TcIL3000_6_1870 ⚠
ubiquitin-protein ligase, putative
— OG7
TcIL3000_10_13390 ⚠
zinc finger protein, putative
— OG7
TcIL3000_0_18230 ⚠
structural maintenance of chromosome 3 , puta
— Both
TcIL3000_10_5760 ⚠
Kinetochore interacting protein 3
— OG7
TcIL3000_6_2060 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcIL3000_8_1450 ⚠
ubiquitin-protein ligase, putative
— OG7
TcIL3000_9_2920 ⚠
adenylate kinase, putative
— OG7
TcIL3000.11.14900 ⚠
ATP-dependent DNA DEAD/DEAH box helicase, put
— OG7
TcIL3000_0_25450 ⚠
SPRY domain containing protein, putative (fra
— OG7
TcIL3000_9_5860 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcIL3000_7_3050 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_8_5130 ⚠
WW domain containing protein, putative
— OG7
TcIL3000_4_260 ⚠
GRIP domain containing protein, putative
— Both
TcIL3000_0_42840 ⚠
hypothetical protein, conserved
— Both
TcIL3000.11.190 ⚠
hypothetical protein, conserved
— Both
TcIL3000_10_9170 ⚠
protein kinase, putative
— Both
TcIL3000_10_9940 ⚠
hypothetical protein, conserved
— Both
TcIL3000.11.4440 ⚠
ATP-dependent RNA helicase, putative
— Both
TcIL3000_10_680 ⚠
adenylate kinase, putative
— Both
TcIL3000_2_1430 ⚠
adenylate kinase, putative
— Both
TcIL3000_7_220 ⚠
FYVE zinc finger, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.