TcIL3000_7_1130

C-1-tetrahydrofolate synthase, cytoplasmic, putative
Trypanosoma congolense IL3000 OG6: OG6_100216 OG7: OG7_0002739 237 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 237 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_10_4190 ⚠
Elongation factor G1, mitochondrial, putative
— Both
TcIL3000_0_14770 ⚠
electron-transfer-flavoprotein, alpha polypep
— Both
TcIL3000.11.8170
predicted WD40 repeat protein
— Both
TcIL3000_2_1210 ⚠
GTP binding protein, putative
— Both
TcIL3000_10_2990 ⚠
aspartate aminotransferase, putative
— Both
TcIL3000.11.5260 ⚠
aspartate aminotransferase, mitochondrial, pu
— Both
TcIL3000_7_2430
translation initiation factor IF-2, putative
— OG6
TcIL3000_2_400
kinetoplast polyadenylation/uridylation facto
— OG6
TcIL3000_7_1550
hypothetical protein, conserved
— OG6
TcIL3000_0_16790 ⚠
calreticulin, putative
— OG6
TcIL3000_8_7620 ⚠
calreticulin, putative
— OG6
TcIL3000_4_4260 ⚠
calreticulin, putative
— OG6
TcIL3000_7_4570
glucosamine-fructose-6-phosphate aminotransfe
— OG6
TcIL3000_0_10000
transaldolase, putative
— Both
TcIL3000.11.7230
hypothetical protein, conserved
— OG6
TcIL3000_7_580
protein kinase C substrate protein, heavy cha
— OG6
TcIL3000_6_2120
importin alpha subunit, putative
— OG6
TcIL3000_8_5630
SMP-30/Gluconolaconase/LRE-like region, putat
— OG6
TcIL3000_8_7150 ⚠
Component of IIS longevity pathway SMK-1, put
— OG6
TcIL3000_7_1410
hypothetical protein, conserved
— OG6
TcIL3000_0_19840 ⚠
hypothetical protein, conserved
— OG6
TcIL3000_8_4880
hypothetical protein, conserved
— Both
TcIL3000_0_33070 ⚠
SET domain containing protein, putative
— OG6
TcIL3000_0_40910 ⚠
SET domain containing protein, putative
— OG6
TcIL3000_0_27490 ⚠
GMP synthase, putative (fragment)
— Both
TcIL3000_0_55050 ⚠
GMP synthase [glutamine-hydrolysing]
— Both
TcIL3000.11.3680
leucyl-tRNA synthetase, putative
— OG6
TcIL3000.11.14520
ubiquitin-conjugating enzyme E2, putative
— Both
TcIL3000.11.7660 ⚠
acidocalcisomal pyrophosphatase
— Both
TcIL3000_9_350 ⚠
Zn-finger in Ran binding protein and others/S
— Both
TcIL3000_10_12020
pyruvate kinase 1, putative
— Both
TcIL3000.11.15410
hypothetical protein, conserved
— Both
TcIL3000_9_3750 ⚠
SET domain containing protein, putative (frag
— OG6
TcIL3000_5_4770 ⚠
hypothetical protein, conserved
— Both
TcIL3000_0_17750 ⚠
Mitochondrial Editosome-like Complex TUTase
— Both
TcIL3000_10_12130
N-myristoyl transferase, putative
— Both
TcIL3000_3_520
NPL4 family, putative
— Both
TcIL3000_0_12320 ⚠
carnitine O-palmitoyltransferase II, putative
— Both
TcIL3000_3_3520 ⚠
tryptophanyl-tRNA synthetase, putative
— OG6
TcIL3000.11.8960 ⚠
haloacid dehalogenase-like hydrolase, putativ
— Both
TcIL3000_5_680 ⚠
monothiol glutaredoxin, putative
— Both
TcIL3000_0_23310 ⚠
KH domain/Domain of unknown function (DUF1771
— Both
TcIL3000_9_3760 ⚠
hypothetical protein
— OG6
TcIL3000_1_790 ⚠
Mitochondrial Editosome-like Complex TUTase
— Both
TcIL3000.11.10550 ⚠
Biotin--acetyl-CoA-carboxylase ligase, putati
— Both
TcIL3000_10_6100
myo-inositol-1-phosphate synthase, putative
— OG6
TcIL3000_5_2540 ⚠
Macro domain containing protein, putative
— Both
TcIL3000.11.110 ⚠
cleavage and polyadenylation specificity fact
— OG6
TcIL3000_0_42430
Flagellum attachment zone protein 19, putativ
— Both
TcIL3000_0_43380 ⚠
UDP-glucose:glycoprotein glucosyltransferase,
— OG6
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.