TcYC6_0016650

serine/threonine protein phosphatase 2A regulatory subunit, putative
Trypanosoma cruzi Y C6 OG6: OG6_101100 OG7: OG7_0004752 48 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 48 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0110800 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
TcYC6_0069510 ⚠
hypothetical protein, conserved
— Both
TcYC6_0115250 ⚠
hypothetical protein, conserved
— Both
TcYC6_0098450
S-adenosylmethionine decarboxylase proenzyme,
— Both
TcYC6_0014120
phosphonopyruvate decarboxylase, putative
— Both
TcYC6_0098790
T-complex protein 11, putative
— Both
TcYC6_0124250
hypothetical protein, conserved
— Both
TcYC6_0013490 ⚠
hypothetical protein, conserved
— Both
TcYC6_0030310
hypothetical protein, conserved
— Both
TcYC6_0096630 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0119750 ⚠
mitochondrial import inner membrane transloca
— OG7
TcYC6_0069680 ⚠
CRAL/TRIO domain containing protein, putative
— OG7
TcYC6_0097500 ⚠
hypothetical protein, conserved
— OG6
TcYC6_0068670 ⚠
TFIIF-stimulated CTD phosphatase, putative
— OG7
TcYC6_0125080 ⚠
NLI interacting factor-like phosphatase, puta
— OG7
TcYC6_0121410 ⚠
nuclear lim interactor-interacting factor, pu
— OG7
TcYC6_0053040 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0006420 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0053050 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0081050 ⚠
poly A polymerase regulatory subunit, putativ
— OG7
TcYC6_0117550 ⚠
NAD binding domain of 6-phosphogluconate dehy
— OG7
TcYC6_0095860 ⚠
dTDP-glucose 4,6-dehydratase, putative
— OG7
TcYC6_0006180 ⚠
glycosyl hydrolase-like protein, putative
— OG7
TcYC6_0024610 ⚠
hypothetical protein
— OG7
TcYC6_0111560
Ubiquitin-like domain containing protein, put
— Both
TcYC6_0036150
hypothetical protein, conserved
— Both
TcYC6_0085920
deoxyhypusine hydroxylase, putative
— Both
TcYC6_0042560 ⚠
methyltransferase domain containing protein,
— Both
TcYC6_0088330
hypothetical protein, conserved
— Both
TcYC6_0118220
peptide chain release factor 1
— Both
TcYC6_0124930
hypothetical protein, conserved
— Both
TcYC6_0045920
hypothetical protein, conserved
— Both
TcYC6_0111310
eukaryotic translation initiation factor 2 su
— Both
TcYC6_0094890 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— Both
TcYC6_0095870 ⚠
adenosine kinase, putative
— Both
TcYC6_0090820 ⚠
adenosine kinase, putative
— Both
TcYC6_0036470
cyclin 1
— Both
TcYC6_0110810
hypothetical protein, conserved
— Both
TcYC6_0058410
hypothetical protein, conserved
— Both
TcYC6_0124410
hypothetical protein, conserved
— Both
TcYC6_0014040
2,3-bisphosphoglycerate-independent phosphogl
— Both
TcYC6_0046610 ⚠
TFIIF-stimulated CTD phosphatase, putative
— Both
TcYC6_0006520 ⚠
Domain of unknown function (DUF3846)/TPR repe
— Both
TcYC6_0080130 ⚠
phosphatidylinositol/phosphatidylcholine tran
— Both
TcYC6_0048920
UDP-sugar pyrophosphorylase
— Both
TcYC6_0093780
WD domain, G-beta repeat, putative
— Both
TcYC6_0098810
DNA ligase I, putative
— Both
TcYC6_0097570 ⚠
hypothetical protein, conserved
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.