TcYC6_0100230

DNA polymerase sigma, putative
Trypanosoma cruzi Y C6 OG6: OG6_101092 OG7: OG7_0003906 49 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 49 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0091400 ⚠
GRIP domain containing protein, putative
— OG7
TcYC6_0000420 ⚠
phosphatidylinositol kinase related protein,
— OG7
TcYC6_0106480 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0025270 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0121990 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
TcYC6_0052770 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
TcYC6_0013660 ⚠
hypothetical protein
— OG7
TcYC6_0069600 ⚠
acyl transferase-like protein
— OG7
TcYC6_0091230 ⚠
target of rapamycin kinase 3
— OG7
TcYC6_0013830 ⚠
hypothetical protein
— OG7
TcYC6_0013700 ⚠
hypothetical protein
— OG7
TcYC6_0091660 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
TcYC6_0017920 ⚠
hypothetical protein
— OG7
TcYC6_0071720 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0114090 ⚠
DNA-directed RNA polymerase III subunit C11,
— OG7
TcYC6_0089250 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0005550 ⚠
Myotubularin-related protein, putative
— OG7
TcYC6_0022910 ⚠
RNA helicase, putative
— OG7
TcYC6_0098800 ⚠
protein mkt1, putative
— OG7
TcYC6_0061110 ⚠
Myotubularin-related protein, putative
— OG7
TcYC6_0016900 ⚠
putative phosphatidylinositol 3-kinase
— OG7
TcYC6_0055570 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
TcYC6_0105090 ⚠
DNA-directed RNA polymerase II subunit RPB1
— OG7
TcYC6_0112480 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
TcYC6_0065700 ⚠
eukaryotic translation initiation factor 2 be
— OG7
TcYC6_0111990
protein kinase
— OG6
TcYC6_0055850 ⚠
Component of motile flagella 6
— Both
TcYC6_0099690 ⚠
RAVE protein 1 C terminal, putative
— Both
TcYC6_0094140 ⚠
hypothetical protein, conserved
— Both
TcYC6_0034400 ⚠
Galactose oxidase, central domain/Kelch motif
— Both
TcYC6_0007860 ⚠
DNA-directed RNA polymerase, putative
— Both
TcYC6_0106680 ⚠
hypothetical protein, conserved
— Both
TcYC6_0096060
RNA-binding protein
— OG6
TcYC6_0056230 ⚠
hypothetical protein, conserved
— Both
TcYC6_0023300 ⚠
hypothetical protein
— Both
TcYC6_0007640 ⚠
glycosyl hydrolase, putative
— Both
TcYC6_0017210 ⚠
exosome-associated protein 1, putative
— Both
TcYC6_0024670 ⚠
putative ribosomal RNA processing protein 40
— Both
TcYC6_0070750 ⚠
pre-RNA processing PIH1/Nop17, putative
— OG7
TcYC6_0116600 ⚠
pre-RNA processing PIH1/Nop17, putative
— OG7
TcYC6_0076120 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0122890 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0044610 ⚠
DNA-direcetd RNA polymerase II, subunit 9, pu
— OG7
TcYC6_0065860 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0072180 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0068310 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0050700 ⚠
CS domain/TPR repeat, putative
— OG7
TcYC6_0056270 ⚠
hypothetical protein, conserved
— OG7
TcYC6_0017900 ⚠
hypothetical protein
— OG7
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.