TvY486_0905210

20S proteasome subunit, (fragment), proteasome beta 2 subunit, putative

Trypanosoma vivax Y486 OG6: OG6_101382 OG7: OG7_0001933 54 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 54 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TvY486_0904170 ⚠ 20S proteasome subunit, proteasome alpha 1 su	—	OG6 LdBPK_353880.1 ↔ LdBPK_354910.1 OG6 TCSYLVIO_005678 ↔ TCSYLVIO_005774 OG7 LdBPK_120030.1 ↔ LdBPK_270190.1 OG7 LdBPK_120030.1 ↔ LdBPK_212070.1 +43 more	Both
TvY486_1000230 ⚠ proteasome alpha 2 subunit, putative	—	OG6 TCSYLVIO_005774 ↔ TCSYLVIO_009369 OG6 LdBPK_212070.1 ↔ LdBPK_353880.1 OG7 LdBPK_120030.1 ↔ LdBPK_270190.1 OG7 LdBPK_120030.1 ↔ LdBPK_212070.1 +43 more	Both
TvY486_0300190 ⚠ proteasome alpha 7 subunit, (fragment)	—	OG6 LdBPK_270190.1 ↔ LdBPK_353880.1 OG7 LdBPK_120030.1 ↔ LdBPK_270190.1 OG7 LdBPK_120030.1 ↔ LdBPK_212070.1 OG7 LdBPK_120030.1 ↔ LdBPK_354910.1 +42 more	Both
TvY486_1107780 ⚠ proteasome beta 3 subunit, putative	—	OG6 LdBPK_280110.1 ↔ LdBPK_353880.1 OG6 TCSYLVIO_001736 ↔ TCSYLVIO_005774 OG7 LdBPK_120030.1 ↔ LdBPK_280110.1 OG7 LdBPK_280110.1 ↔ LdBPK_353880.1 +5 more	Both
TvY486_1000170 ⚠ proteasome subunit alpha type-5, putative	—	OG6 LdBPK_212200.1 ↔ LdBPK_353880.1 OG7 LdBPK_120030.1 ↔ LdBPK_270190.1 OG7 LdBPK_120030.1 ↔ LdBPK_212070.1 OG7 LdBPK_120030.1 ↔ LdBPK_354910.1 +42 more	Both
TvY486_0704848 ⚠ 20S proteasome beta 6 subunit, putative, prot	—	OG6 LdBPK_060140.1 ↔ LdBPK_353880.1 OG7 TCSYLVIO_002482 ↔ TCSYLVIO_006999 OG7 LdBPK_060140.1 ↔ LdBPK_120030.1 OG7 LdBPK_060140.1 ↔ LdBPK_353880.1 +3 more	Both
TvY486_0704860 ⚠ proteasome beta 6 subunit, putative, 20S prot	—	OG6 LdBPK_060140.1 ↔ LdBPK_353880.1 OG7 TCSYLVIO_002482 ↔ TCSYLVIO_006999 OG7 LdBPK_060140.1 ↔ LdBPK_120030.1 OG7 LdBPK_060140.1 ↔ LdBPK_353880.1 +3 more	Both
TvY486_0704500 ⚠ proteasome alpha 3 subunit, putative	—	OG6 LdBPK_140310.1 ↔ LdBPK_353880.1 OG7 LdBPK_120030.1 ↔ LdBPK_270190.1 OG7 LdBPK_120030.1 ↔ LdBPK_212070.1 OG7 LdBPK_120030.1 ↔ LdBPK_354910.1 +42 more	Both
TvY486_0600770 ⚠ proteasome beta-1 subunit, putative	—	OG6 LdBPK_120030.1 ↔ LdBPK_353880.1 OG6 TCSYLVIO_005774 ↔ TCSYLVIO_006999 OG7 LdBPK_120030.1 ↔ LdBPK_353880.1 OG7 LdBPK_120030.1 ↔ LdBPK_361730.1 +3 more	Both
TvY486_1004750 ⚠ proteasome subunit beta type-2, putative	—	OG6 LdBPK_353880.1 ↔ LdBPK_360340.1 OG7 LdBPK_120030.1 ↔ LdBPK_360340.1 OG7 LdBPK_353880.1 ↔ LdBPK_360340.1 OG7 Tb927.10.4710 ↔ Tb927.10.6080 +3 more	Both
TvY486_1107320 ⚠ proteasome alpha 7 subunit, putative, (fragme	—	OG6 LdBPK_110240.1 ↔ LdBPK_353880.1 OG6 TCSYLVIO_001707 ↔ TCSYLVIO_005774 OG7 LdBPK_120030.1 ↔ LdBPK_270190.1 OG7 LdBPK_120030.1 ↔ LdBPK_212070.1 +43 more	Both
TvY486_1005980 ⚠ proteasome subunit alpha type-1, putative	—	OG6 LdBPK_353880.1 ↔ LdBPK_361670.1 OG7 LdBPK_120030.1 ↔ LdBPK_270190.1 OG7 LdBPK_120030.1 ↔ LdBPK_212070.1 OG7 LdBPK_120030.1 ↔ LdBPK_354910.1 +42 more	Both
TvY486_1006040 ⚠ proteasome subunit beta type-5, putative	—	OG6 LdBPK_353880.1 ↔ LdBPK_361730.1 OG7 LdBPK_120030.1 ↔ LdBPK_353880.1 OG7 LdBPK_120030.1 ↔ LdBPK_361730.1 OG7 LdBPK_353880.1 ↔ LdBPK_361730.1 +2 more	Both
TvY486_1116860 ⚠ proteasome regulatory non-ATP-ase subunit 7,	—	OG7 Tb927.10.6080 ↔ Tb927.11.16030	OG7
TvY486_0905200 ⚠ T-complex protein 1, eta subunit, putative, t	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_006999 +2 more	OG7
TvY486_1103330 ⚠ T-complex protein 1, zeta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_006999 +2 more	OG7
TvY486_1008070 ⚠ T-complex protein 1, theta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_006999 +2 more	OG7
TvY486_1007260 ⚠ ATP-dependent DEAD/H RNA helicae, putative	—	OG7 TCSYLVIO_004479 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004479 ↔ TCSYLVIO_006999	OG7
TvY486_1101820 ⚠ T-complex protein 1, beta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_006999 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_006999 +2 more	OG7
TvY486_0805880 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_001310 ↔ TCSYLVIO_004939	OG7
TvY486_0401570 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_003828 ↔ TCSYLVIO_004939	OG7
TvY486_1113090 ⚠ flagellar pocket cytoskeletal protein bilbo1	—	OG7 TCSYLVIO_004939 ↔ TCSYLVIO_006469	OG7
TvY486_0801090 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_004939 ↔ TCSYLVIO_009798	OG7
TvY486_1114340 ⚠ paraflagellar rod component, putative (fragme	—	OG7 TCSYLVIO_004939 ↔ TCSYLVIO_006797	OG7
TvY486_0704800 ⚠ ribosomal RNA processing protein 4, putative	—	OG7 TCSYLVIO_004939 ↔ TCSYLVIO_010369	OG7
TvY486_0502990 ⚠ delta-adaptin, putative	—	OG7 TCSYLVIO_004939 ↔ TCSYLVIO_010530	OG7
TvY486_1014740 ⚠ DNA-directed RNA polymerases I and III subuni	—	OG7 TCSYLVIO_004939 ↔ TCSYLVIO_010718	OG7
TvY486_0304910 ⚠ DNA-directed RNA polymerase II subunit 3, put	—	OG7 TCSYLVIO_004939 ↔ TCSYLVIO_010718	OG7
TvY486_1100580 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_004939 ↔ TCSYLVIO_007412	OG7
TvY486_0502575 ⚠ ribose-phosphate pyrophosphokinase, putative,	—	OG7 TCSYLVIO_006999 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_005774 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_006999	OG7
TvY486_0400130 ⚠ proteasome beta 7 subunit	—	OG7 Tb927.4.430 ↔ Tb927.6.1260 OG7 Tb927.10.6080 ↔ Tb927.4.430	OG7
TvY486_0901460 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_003433 ↔ TCSYLVIO_004939	OG7
TvY486_0700580 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_002300 ↔ TCSYLVIO_004939	OG7
TvY486_1117570 ⚠ exosome-associated protein 2, putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004939 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_006999	Both
TvY486_0303280 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_004312 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004312 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004312 ↔ TCSYLVIO_006999	Both
TvY486_0201510 ⚠ Phosducin, putative	—	OG6 TCSYLVIO_000453 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_006999	Both
TvY486_1117000 ⚠ ATP binding protein-like protein, putative	—	OG6 TCSYLVIO_000453 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_006999	Both
TvY486_0301890 ⚠ ATP-dependent DEAD/H RNA helicase, putative	—	OG6 TCSYLVIO_004479 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004479 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004479 ↔ TCSYLVIO_006999	Both
TvY486_0401320 ⚠ ribosomal RNA processing protein 6, putative	—	OG6 TCSYLVIO_003804 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_003804 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_003804 ↔ TCSYLVIO_006999	Both
TvY486_1009350 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG6 TCSYLVIO_004731 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_006999 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_005774 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_005774 +1 more	Both
TvY486_1103090 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG6 TCSYLVIO_004731 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_006999 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_005774 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_005774 +1 more	Both
TvY486_1107270 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001704 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_001704 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_001704 ↔ TCSYLVIO_006999	Both
TvY486_0802590 ⚠ chaperonin/T-complex protein 1 gamma subunit,	—	OG6 TCSYLVIO_000177 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_006999 +3 more	Both
TvY486_0029620 ⚠ chaperonin containing t-complex protein, puta	—	OG6 TCSYLVIO_000177 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_006999 +3 more	Both
TvY486_1001550 ⚠ proteasome regulatory non-ATP-ase subunit 5,	—	OG7 Tb927.10.1550 ↔ Tb927.6.1260	OG7
TvY486_0600170 ⚠ exosome complex exonuclease, ribosomal RNA pr	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004939 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_006999	Both
TvY486_1003140 ⚠ acetyltransferase, putative	—	OG6 TCSYLVIO_004519 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004519 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004519 ↔ TCSYLVIO_006999	Both
TvY486_1001000 ⚠ T-complex protein 1, delta subunit, putative	—	OG6 TCSYLVIO_005774 ↔ TCSYLVIO_008271 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_005312 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_006999 +3 more	Both
TvY486_0502330 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG6 TCSYLVIO_005774 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_006999 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_005774 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004731 ↔ TCSYLVIO_005774 +1 more	Both
TvY486_0703780 ⚠ 'Cold-shock' DNA-binding domain containing pr	—	OG6 TCSYLVIO_005774 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_006999 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_005774 ↔ TCSYLVIO_010606	Both

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