LAEL147_000413200

Cullin family/Cullin protein neddylation domain containing protein, putative
Leishmania aethiopica L147 OG6: OG6_168578 OG7: OG7_0001577 136 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 136 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000636100 ⚠
DEAD/DEAH box helicase-like protein, putative
— OG7
LAEL147_000369300 ⚠
DNA polymerase theta (helicase domain only),
— OG7
LAEL147_000177000 ⚠
ATP-dependent RNA helicase, putative
— Both
LAEL147_000251900 ⚠
ATP-dependent RNA helicase, putative
— Both
LAEL147_000264000 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LAEL147_000214900 ⚠
hypothetical protein, conserved
— Both
LAEL147_000106200 ⚠
ribose-phosphate pyrophosphokinase, putative
— Both
LAEL147_000371100 ⚠
Csl4p homologue, putative
— Both
LAEL147_000228400 ⚠
tubulin tyrosine ligase, putative
— Both
LAEL147_000351700 ⚠
Concanavalin A-like lectin/glucanases superfa
— Both
LAEL147_000501800 ⚠
AARP2CN (NUC121) domain/Protein of unknown fu
— OG7
LAEL147_000292700 ⚠
DNA-directed RNA polymerase polypeptide, puta
— OG7
LAEL147_000587800 ⚠
DNA-directed RNA polymerase polypeptide, puta
— OG7
LAEL147_000252000 ⚠
formin, putative
— OG7
LAEL147_000111300 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
LAEL147_000868200 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LAEL147_000686900 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LAEL147_000262000 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LAEL147_000150000 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LAEL147_000653100 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LAEL147_000801500 ⚠
tubulin tyrosine ligase, putative
— OG7
LAEL147_000570600 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LAEL147_000517200 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LAEL147_000480700 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LAEL147_000301600 ⚠
tubulin-tyrosine ligase, putative
— OG7
LAEL147_000748300 ⚠
phosphatidylinositol 3-kinase (tor2), putativ
— OG7
LAEL147_000786400 ⚠
zinc finger protein, putative
— OG7
LAEL147_000607700 ⚠
polyubiquitin, putative
— OG7
LAEL147_000636700 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LAEL147_000534700 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
LAEL147_000653400 ⚠
DNA replication licensing factor MCM7, putati
— OG7
LAEL147_000813900 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
LAEL147_000062700 ⚠
DNA replication licensing factor MCM8, putati
— OG7
LAEL147_000695500 ⚠
DNA replication licensing factor MCM3, putati
— OG7
LAEL147_000507600 ⚠
DNA replication licensing factor MCM6, putati
— OG7
LAEL147_000438300 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAEL147_000426600 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAEL147_000821900 ⚠
adenylate kinase, putative
— OG7
LAEL147_000826100 ⚠
neurobeachin/beige protein, putative
— OG7
LAEL147_000696400 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LAEL147_000373200 ⚠
neutral sphingomyelinase activation associate
— OG7
LAEL147_000014400 ⚠
RNA polymerase ii largest subunit
— OG7
LAEL147_000706300 ⚠
RNA polymerase ii largest subunit
— OG7
LAEL147_000702100 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000224500 ⚠
AAA domain containing protein, putative
— OG7
LAEL147_000786500 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LAEL147_000762900 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000063400 ⚠
structural maintenance of chromosome (SMC), p
— OG7
LAEL147_000327600 ⚠
RecF/RecN/SMC N terminal domain/SMC proteins
— OG7
LAEL147_000635700 ⚠
RNA guanylyltransferase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.