LAEL147_000527500

hypothetical protein, conserved
Leishmania aethiopica L147 OG6: OG6_200029 OG7: OG7_0051972 119 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 119 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000507700 ⚠
WW domain containing protein, putative
— OG7
LAEL147_000282000 ⚠
kinesin, putative
— OG6
LAEL147_000282100 ⚠
kinesin, putative
— OG6
LAEL147_000419400
Not1 N-terminal domain, CCR4-Not complex comp
— Both
LAEL147_000395400
hypothetical protein, conserved
— Both
LAEL147_000216400
hypothetical protein, conserved
— Both
LAEL147_000525400
kinesin, putative
— OG6
LAEL147_000200600
tc40 antigen-like
— Both
LAEL147_000065800
Ankyrin repeats (many copies)/Ankyrin repeats
— Both
LAEL147_000168000 ⚠
WW domain containing protein, putative
— Both
LAEL147_000445600 ⚠
microtubule-associated protein, putative
— Both
LAEL147_000169100 ⚠
TPR repeat/Tetratricopeptide repeat, putative
— Both
LAEL147_000348200
ATP-dependent DEAD/H RNA helicase, putative
— OG6
LAEL147_000458000
nucleoporin, putative
— Both
LAEL147_000339700
proteasome regulatory ATPase subunit 1, putat
— OG6
LAEL147_000084900
hypothetical protein, conserved
— Both
LAEL147_000161800 ⚠
translation initiation factor EIF-2b alpha su
— Both
LAEL147_000240600 ⚠
WD domain, G-beta repeat, putative
— OG7
LAEL147_000141500 ⚠
Translation initiation factor eIF-2B subunit
— OG7
LAEL147_000700200 ⚠
46 kD virulence factor
— OG7
LAEL147_000700300 ⚠
hypothetical protein
— OG7
LAEL147_000070300 ⚠
MORN repeat, putative
— OG7
LAEL147_000727700 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LAEL147_000726600 ⚠
Sec7 domain containing protein, putative
— OG7
LAEL147_000556500 ⚠
ubiquitin-protein ligase, putative
— OG7
LAEL147_000235700 ⚠
WW domain containing protein, putative
— OG7
LAEL147_000558400 ⚠
WW domain containing protein, putative
— OG7
LAEL147_000558500 ⚠
hypothetical protein
— OG7
LAEL147_000063500 ⚠
Tetratricopeptide repeat/TPR repeat, putative
— OG7
LAEL147_000028500
hypothetical protein, conserved
— OG7
LAEL147_000864200 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000663900 ⚠
cAMP response protein, putative
— OG7
LAEL147_000731300 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LAEL147_000174700 ⚠
protein kinase A regulatory subunit, putative
— OG7
LAEL147_000101000 ⚠
adaptor complex protein (AP) 3 delta subunit
— OG7
LAEL147_000786500 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LAEL147_000254500 ⚠
5'-3' exonuclease, putative
— OG7
LAEL147_000474300
hypothetical protein, conserved
— OG7
LAEL147_000038600 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000038500 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAEL147_000511400 ⚠
gamma-tubulin complex subunit, putative
— OG7
LAEL147_000330500 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
LAEL147_000187300 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LAEL147_000727200 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000039000 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000283300
signal recognition particle protein, putative
— OG7
LAEL147_000842000 ⚠
exosome complex exonuclease RRP41, putative
— OG7
LAEL147_000862700 ⚠
exosome-associated protein 4, putative
— OG7
LAEL147_000838300
hypothetical protein, conserved
— OG7
LAEL147_000262900 ⚠
tubulin-specific chaperone, putative
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.