LAEL147_000655500

Serine hydrolase (FSH1)/RWD domain/50S ribosome-binding GTPase/GTPase of unknown function C-terminal, putative
Leishmania aethiopica L147 OG6: OG6_105111 OG7: OG7_0003363 55 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 55 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000499700 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000851100 ⚠
glycyl tRNA synthetase, putative
— OG7
LAEL147_000794800 ⚠
predicted zinc finger protein
— OG7
LAEL147_000578100 ⚠
glyceraldehyde 3-phosphate dehydrogenase, gly
— OG7
LAEL147_000335400 ⚠
glutamine amidotransferase, putative
— OG7
LAEL147_000708700 ⚠
Gamma-soluble NSF attachment protein (SNAP-ga
— OG7
LAEL147_000457500 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000882900 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000643300 ⚠
cytidyltransferase-like domain containing pro
— OG7
LAEL147_000337700 ⚠
Tetrahydrofolate dehydrogenase/cyclohydrolase
— OG7
LAEL147_000640600 ⚠
iron superoxide dismutase, putative
— OG7
LAEL147_000284400 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAEL147_000689500 ⚠
WD domain, G-beta repeat, putative
— OG7
LAEL147_000240000 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000264000 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LAEL147_000062600 ⚠
monothiol glutaredoxin, putative
— OG7
LAEL147_000109100 ⚠
mitochondrial DNA polymerase beta
— OG7
LAEL147_000224700 ⚠
2OG-Fe(II) oxygenase superfamily, putative
— OG7
LAEL147_000428800 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— OG7
LAEL147_000103900 ⚠
iron superoxide dismutase
— OG7
LAEL147_000675200 ⚠
nicotinate phosphoribosyltransferase, putativ
— OG7
LAEL147_000742100 ⚠
phosphomannomutase-like protein
— OG7
LAEL147_000316800 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000337600 ⚠
methylenetetrahydrofolate dehydrogenase-like
— OG7
LAEL147_000799800 ⚠
glyceraldehyde-3-phosphate dehydrogenase-like
— OG7
LAEL147_000583000 ⚠
WD domain, G-beta repeat, putative
— OG7
LAEL147_000109200 ⚠
mitochondrial DNA polymerase beta-PAK, putati
— OG7
LAEL147_000035800 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000767200 ⚠
ubiquitin hydrolase, putative
— OG7
LAEL147_000221000 ⚠
ubiquitin hydrolase, putative
— OG7
LAEL147_000076200 ⚠
glutamine synthetase, putative
— OG7
LAEL147_000786400 ⚠
zinc finger protein, putative
— OG7
LAEL147_000261200 ⚠
Dephospho-CoA kinase, putative
— OG7
LAEL147_000649700 ⚠
superoxide dismutase, putative
— OG7
LAEL147_000795000 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000851500 ⚠
eukaryotic translation initiation factor 3 su
— OG7
LAEL147_000632900 ⚠
exportin 1, putative
— OG7
LAEL147_000481800 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000351600 ⚠
GDP-mannose pyrophosphorylase
— OG7
LAEL147_000020000 ⚠
monothiol glutaredoxin, putative
— OG7
LAEL147_000659000 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000439900 ⚠
MORN repeat/FYVE zinc finger containing prote
— OG7
LAEL147_000161900 ⚠
PITH domain containing protein, putative
— OG7
LAEL147_000876600 ⚠
Sucrase/ferredoxin-like, putative
— OG7
LAEL147_000745300 ⚠
ubiquitin hydrolase, putative
— OG7
LAEL147_000467700 ⚠
WD domain, G-beta repeat, putative
— OG7
LAEL147_000438300 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAEL147_000426600 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAEL147_000204100 ⚠
ras-like small GTPases, putative
— OG7
LAEL147_000284700 ⚠
WD domain, G-beta repeat, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.