LAMA_000201800

hypothetical protein, conserved
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_139746 OG7: OG7_0042831 44 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 44 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000809200 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000597100 ⚠
WW domain containing protein, putative
— OG7
LAMA_000097400 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000253000 ⚠
WW domain containing protein, putative
— OG7
LAMA_000279600 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000090400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000515800 ⚠
MORN repeat/FYVE zinc finger containing prote
— OG7
LAMA_000820400 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LAMA_000713100 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG7
LAMA_000641300 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LAMA_000740500 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LAMA_000425600 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000613700 ⚠
Rab-GTPase-TBC domain containing protein, put
— OG7
LAMA_000298800 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000801700 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000574900 ⚠
Protein kinase domain/Protein tyrosine kinase
— OG7
LAMA_000514200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000221900 ⚠
FYVE zinc finger/Ras family, putative
— OG7
LAMA_000235800
Rad9, putative
— OG7
LAMA_000310500 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LAMA_000396800 ⚠
Protein tyrosine kinase/Protein kinase domain
— OG7
LAMA_000557900 ⚠
Rrp44-like cold shock domain/Dis3-like cold-s
— OG7
LAMA_000273400 ⚠
Rab-GTPase-TBC domain containing protein, put
— Both
LAMA_000732600 ⚠
Deoxyhypusine synthase, putative
— Both
LAMA_000334600
hypothetical protein, conserved
— Both
LAMA_000108200 ⚠
Protein kinase domain/Protein tyrosine kinase
— Both
LAMA_000380800 ⚠
Deoxyhypusine synthase, putative
— Both
LAMA_000817100
bacteroidetes VLRF1 release factor, putative
— Both
LAMA_000595400 ⚠
HECT-domain (ubiquitin-transferase), putative
— Both
LAMA_000279000 ⚠
Zn-finger in Ran binding protein and others/F
— Both
LAMA_000232500
hypothetical protein, conserved
— Both
LAMA_000282000
Cyclophilin type peptidyl-prolyl cis-trans is
— OG6
LAMA_000384900
hypothetical protein, conserved
— Both
LAMA_000171000
GRIP domain containing protein, putative
— Both
LAMA_000112500
XPC-binding domain/UBA/TS-N domain containing
— Both
LAMA_000279900
hypothetical protein, conserved
— Both
LAMA_000261200 ⚠
Dihydrouridine synthase (Dus), putative
— Both
LAMA_000178900
Leucine Rich repeat, putative
— Both
LAMA_000083600
SIS domain containing protein, putative
— Both
LAMA_000526200
hypothetical protein, conserved
— Both
LAMA_000514500
Cupin-like domain containing protein, putativ
— Both
LAMA_000432800
tRNA synthetases class II (A)/Threonyl and Al
— Both
LAMA_000559100 ⚠
RNB domain containing protein, putative
— Both
LAMA_000053300 ⚠
RNB domain containing protein, putative
— OG7
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.