LINF_220022100

exosome complex exonuclease RRP45 homolog - putative

Leishmania infantum JPCM5 OG6: OG6_100420 OG7: OG7_0002825 66 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Interactions 66 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LINF_140005000 ⚠ exosome complex exonuclease - putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_010369 OG6 Tb927.6.670 ↔ Tb927.7.4670 OG6 Tb927.11.16600 ↔ Tb927.7.4670 OG6 LdBPK_140010.1 ↔ LdBPK_221430.1 +4 more	Both
LINF_020008200 ⚠ RNase PH-like protein - putative	—	OG6 LdBPK_020290.1 ↔ LdBPK_221430.1 OG6 Tb927.11.16600 ↔ Tb927.2.2180 OG7 Tb927.11.16600 ↔ Tb927.2.2180 OG7 Tb927.10.7450 ↔ Tb927.6.670 +2 more	Both
LINF_040006300 ⚠ exosome complex exonuclease RRP40 - putative	—	OG6 LdBPK_040130.1 ↔ LdBPK_221430.1 OG6 Tb927.6.670 ↔ Tb927.9.7070 OG6 Tb927.11.16600 ↔ Tb927.9.7070 OG7 Tb927.6.670 ↔ Tb927.9.7070 +2 more	Both
LINF_340037900 ⚠ exosome subunit rrp6p homologue - putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_003804 OG6 LdBPK_044330.1 ↔ LdBPK_221430.1 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_003804 OG7 LdBPK_044330.1 ↔ LdBPK_221430.1	Both
LINF_360058400 ⚠ exosome-associated protein 4 - putative	—	OG7 Tb927.11.16600 ↔ Tb927.2.2180 OG7 Tb927.10.7450 ↔ Tb927.6.670 OG7 Tb927.10.7450 ↔ Tb927.11.16600 OG7 LdBPK_020290.1 ↔ LdBPK_221430.1	OG7
LINF_340037400 ⚠ exosome subunit rrp6p homologue - putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_003804 OG6 LdBPK_044330.1 ↔ LdBPK_221430.1 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_003804 OG7 LdBPK_044330.1 ↔ LdBPK_221430.1	Both
LINF_360038200 ⚠ exosome complex exonuclease RRP41A	—	OG6 Tb927.10.7450 ↔ Tb927.6.670 OG6 Tb927.10.7450 ↔ Tb927.11.16600 OG7 Tb927.11.16600 ↔ Tb927.2.2180 OG7 Tb927.10.7450 ↔ Tb927.6.670 +2 more	Both
LINF_230024800 ⚠ exosome component CSL4 - putative	—	OG6 Tb927.11.16600 ↔ Tb927.5.1200 OG6 Tb927.5.1200 ↔ Tb927.6.670 OG7 Tb927.11.16600 ↔ Tb927.5.1200 OG7 Tb927.5.1200 ↔ Tb927.6.670	Both
LINF_110007300 ⚠ proteasome alpha 7 subunit - putative	—	OG6 TCSYLVIO_001707 ↔ TCSYLVIO_001893 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_001893	Both
LINF_280006000 ⚠ proteasome beta 3 subunit - putative	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_001893 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_001893	Both
LINF_340014000 ⚠ elongation factor 1-beta	—	OG6 Tb927.10.5840 ↔ Tb927.6.670 OG6 Tb927.10.5840 ↔ Tb927.11.16600 OG7 Tb927.10.5840 ↔ Tb927.6.670 OG7 Tb927.10.5840 ↔ Tb927.11.16600	Both
LINF_340014200 ⚠ elongation factor 1-beta	—	OG6 Tb927.10.5840 ↔ Tb927.6.670 OG6 Tb927.10.5840 ↔ Tb927.11.16600 OG7 Tb927.10.5840 ↔ Tb927.6.670 OG7 Tb927.10.5840 ↔ Tb927.11.16600	Both
LINF_360020500 ⚠ translation elongation factor 1-beta - putati	—	OG6 Tb927.10.5840 ↔ Tb927.6.670 OG6 Tb927.10.5840 ↔ Tb927.11.16600 OG7 Tb927.10.5840 ↔ Tb927.6.670 OG7 Tb927.10.5840 ↔ Tb927.11.16600	Both
LINF_350028000 ⚠ ATP-dependent RNA helicase-like protein	—	OG6 TCSYLVIO_001373 ↔ TCSYLVIO_001893	OG6
LINF_110007500 ⚠ hypothetical protein - conserved	—	OG6 TCSYLVIO_001704 ↔ TCSYLVIO_001893 OG7 TCSYLVIO_001704 ↔ TCSYLVIO_001893	Both
LINF_010010700 ⚠ pre-mRNA processing factor 3 (PRP3)/Protein o	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_003433 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_003433	Both
LINF_350043800 ⚠ proteasome beta 2 subunit - putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004939 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_006999	Both
LINF_290021000 ⚠ hypothetical protein - conserved	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_004312 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004312	Both
LINF_340034000 ⚠ hypothetical protein - conserved	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_003828 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_003828	Both
LINF_320042100 ⚠ exosome-associated protein 2 - putative	—	OG6 Tb927.11.16600 ↔ Tb927.6.670 OG7 Tb927.11.16600 ↔ Tb927.6.670	Both
LINF_210026800 ⚠ proteasome alpha 2 subunit - putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_001893	Both
LINF_200005000 ⚠ DNA-directed RNA polymerase II subunit 2 - pu	—	OG7 Tb927.11.16600 ↔ Tb927.11.630 OG7 Tb927.11.630 ↔ Tb927.6.670	OG7
LINF_260009800 ⚠ Conserved hypothetical ATP binding protein -	—	OG7 Tb927.11.16600 ↔ Tb927.3.1150 OG7 Tb927.3.1150 ↔ Tb927.6.670	OG7
LINF_310006600 ⚠ DNA-directed RNA polymerase II subunit 2 - pu	—	OG7 Tb927.11.16600 ↔ Tb927.11.630 OG7 Tb927.11.630 ↔ Tb927.6.670	OG7
LINF_270019000 ⚠ T-complex protein 1 - beta subunit - putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_008271 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001893	OG7
LINF_270006800 ⚠ proteasome alpha 7 subunit - putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_001893	OG7
LINF_360022300 ⚠ proteasome subunit alpha type-1 - putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_001893	OG7
LINF_210028100 ⚠ proteasome subunit alpha type-5 - putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_001893	OG7
LINF_130022100 ⚠ chaperonin TCP20 - putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_008271 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001893	OG7
LINF_190011500 ⚠ DNA-directed RNA polymerases I and III subuni	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_010718	OG7
LINF_140008100 ⚠ proteasome alpha 3 subunit - putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_001893	OG7
LINF_360081100 ⚠ T-complex protein 1 - theta subunit - putativ	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_008271 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001893	OG7
LINF_350044000 ⚠ T-complex protein 1 - eta subunit - putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_008271 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001893	OG7
LINF_360038000 ⚠ ATP-dependent RNA helicase - putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004479	OG7
LINF_080010200 ⚠ ribose-phosphate pyrophosphokinase - putative	—	OG7 TCSYLVIO_001893 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004731	OG7
LINF_300018400 ⚠ hypothetical protein - conserved	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_003184 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_003184	Both
LINF_180019100 ⚠ heat shock protein 110 - putative	—	OG6 Tb927.10.12710 ↔ Tb927.6.670	OG6
LINF_320037000 ⚠ ATP binding protein-like protein	—	OG6 TCSYLVIO_000453 ↔ TCSYLVIO_001893 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_001893	Both
LINF_270029200 ⚠ Phosducin/Thioredoxin - putative	—	OG6 TCSYLVIO_000453 ↔ TCSYLVIO_001893 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_001893	Both
LINF_250011500 ⚠ RNA polymerase I second largest subunit - put	—	OG6 Tb927.11.630 ↔ Tb927.6.670 OG6 Tb927.11.16600 ↔ Tb927.11.630 OG7 Tb927.11.16600 ↔ Tb927.11.630 OG7 Tb927.11.630 ↔ Tb927.6.670	Both
LINF_250018800 ⚠ hypothetical protein - conserved	—	OG6 Tb927.3.1300 ↔ Tb927.6.670 OG6 Tb927.11.16600 ↔ Tb927.3.1300 OG7 Tb927.11.16600 ↔ Tb927.3.1300 OG7 Tb927.3.1300 ↔ Tb927.6.670	Both
LINF_250020100 ⚠ Conserved hypothetical ATP binding protein -	—	OG6 Tb927.3.1150 ↔ Tb927.6.670 OG6 Tb927.11.16600 ↔ Tb927.3.1150 OG7 Tb927.11.16600 ↔ Tb927.3.1150 OG7 Tb927.3.1150 ↔ Tb927.6.670	Both
LINF_320015700 ⚠ chaperonin containing t-complex protein - put	—	OG6 TCSYLVIO_000177 ↔ TCSYLVIO_001893 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_008271 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001893	Both
LINF_230021100 ⚠ T-complex protein 1 - gamma subunit - putativ	—	OG6 TCSYLVIO_000177 ↔ TCSYLVIO_001893 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_008271 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001893	Both
LINF_200018800 ⚠ RNasePH-like protein	—	OG6 Tb927.1.2580 ↔ Tb927.6.670 OG6 Tb927.1.2580 ↔ Tb927.11.16600 OG7 Tb927.1.2580 ↔ Tb927.6.670 OG7 Tb927.1.2580 ↔ Tb927.11.16600	Both
LINF_080016200 ⚠ phosphoribosylpyrophosphate synthetase	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004731	Both
LINF_210018500 ⚠ T-complex protein 1 - delta subunit - putativ	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_008271 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_008271 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_001893	Both
LINF_080005800 ⚠ adaptor complex protein (AP) 3 delta subunit	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_010530 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_010530	Both
LINF_030006100 ⚠ acetyltransferase - putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_004519 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004519	Both
LINF_030011900 ⚠ DEAD/DEAH box helicase/Type III restriction e	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_004479 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004479	Both

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